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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">fcmedicine</journal-id><journal-title-group><journal-title xml:lang="ru">Фундаментальная и клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Fundamental and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2500-0764</issn><issn pub-type="epub">2542-0941</issn><publisher><publisher-name>КемГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23946/2500-0764-2025-10-2-15-31</article-id><article-id custom-type="elpub" pub-id-type="custom">fcmedicine-1016</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭПИДЕМИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EPIDEMIOLOGY</subject></subj-group></article-categories><title-group><article-title>Роль клинических рекомендаций по профилактике и лечению сердечно-сосудистых заболеваний в снижении бремени болезней системы кровообращения</article-title><trans-title-group xml:lang="en"><trans-title>The role of clinical guidelines in reducing the burden of cardiovascular diseases.</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4146-4787</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полибин</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Polibin</surname><given-names>R. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полибин Роман Владимирович, кандидат медицинских наук, доцент, заместитель директора по научной работе Института общественного здоровья им. Ф. Ф. Эрисмана, доцент кафедры эпидемиологии и доказательной медицины</p><p>ул. Трубецкая, д. 8, стр. 2, г. Москва, 119048</p></bio><bio xml:lang="en"><p>Dr. Roman V. Polibin, MD, Cand. Sci. (Medicine), Chief Scientific Officer, Erismann Institute of Public Health; Associate Professor, Department of Epidemiology and Evidence-based Medicine</p><p>Trubetskaya Street, 8, Building 2, Moscow, 119048</p></bio><email xlink:type="simple">polibin_r_v@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2121-4975</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петухова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Petukhova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петухова Ирина Вячеславовна, ординатор кафедры эпидемиологии и доказательной медицины</p><p>ул. Трубецкая, д. 8, стр. 2, г. Москва, 119048</p></bio><bio xml:lang="en"><p>Dr. Irina V. Petukhova, MD, Clinical Resident, Department of Epidemiology and Evidence-Based Medicine</p><p>Trubetskaya Street, 8, Building 2, Moscow, 119048</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2025</year></pub-date><volume>10</volume><issue>2</issue><fpage>15</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Полибин Р.В., Петухова И.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Полибин Р.В., Петухова И.В.</copyright-holder><copyright-holder xml:lang="en">Polibin R.V., Petukhova I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://fcm.kemsmu.ru/jour/article/view/1016">https://fcm.kemsmu.ru/jour/article/view/1016</self-uri><abstract><p>Цель. Оценить влияние внедрения во врачебную практику клинических рекомендаций (КР) по кардиологии в Российской Федерации (РФ) и некоторых странах Европейского региона на динамику смертности от сердечно-сосудистых заболеваний (ССЗ). Материалы и методы. Выборка данных о смертности от ССЗ была проведена с использованием базы данных Global Burden of Disease. Распределение стран на 5 кластеров по уровню смертности осуществлялось с помощью кластерного анализа. Информация об используемых КР была получена на сайтах профессиональных сообществ и по данным российских и зарубежных публикаций. Проведен эпидемиологический анализ смертности от ССЗ в периоды до и после внедрения КР. Проведены оценка динамики смертности и сравнение темпов прироста до и после внедрения КР. Результаты. После внедрения КР выявлено снижение смертности в Испании, Эстонии, России, Латвии, Республике Беларусь, Украине и более выраженный темп снижения в Великобритании и Нидерландах. Снижение смертности в Бельгии, Франции, Словакии, Италии, Португалии, Германии, Чехии обусловлено успешно реализуемыми кампаниями по профилактике ССЗ, внедрению и использованию КР в медицинской практике. Рост смертности в Хорватии, Сербии, Боснии и Герцеговине, Литве, Румынии и Болгарии связан с ограниченными экономическими возможностями, препятствующими полноценной реализации превентивных и лечебных программ. Заключение. Внедрение КР по ССЗ в систему здравоохранения сыграло важную роль в снижении смертности. Для достижения максимального эффекта от внедрения КР во врачебную практику необходима комплексная стратегия, обеспечивающая доступность качественной медицинской помощи для всего населения, в том числе программ профилактики и реабилитации, достаточный объем финансирования, включая современное оснащение медицинских организаций, подготовку и повышение уровня квалификации медицинских кадров. Лишь при условии интеграции КР в систему здравоохранения с обеспечением реализации изложенных в них направлений профилактики, диагностики и лечения можно достичь значительного снижения заболеваемости и смертности от ССЗ</p></abstract><trans-abstract xml:lang="en"><p>Aim. To assess the impact of implementing evidencebased cardiology guidelines into the clinical practice in the Russian Federation and selected European countries on trends in cardiovascular disease (CVD) mortality. Materials and Methods. Mortality data were obtained from the Global Burden of Disease database. Countries were grouped into five clusters based on CVD mortality rates. Information on implemented clinical guidelines was gathered from professional society websites and published national and international sources. We further conduced an epidemiological analysis of CVD mortality before and after the implementation of clinical guidelines, including before-after analysis of mortality trends. Results. After the implementation of clinical cardiology guidelines, a reduction in CVD mortality was observed in Spain, Estonia, Russia, Latvia, Belarus, Ukraine, and especially United Kingdom and the Netherlands. Decrease in mortality in Belgium, France, Slovakia, Italy, Portugal, Germany, and the Czech Republic was associated with successful CVD prevention campaigns and active use of clinical cardiology guidelines in clinical practice. Increased mortality in Croatia, Serbia, Bosnia and Herzegovina, Lithuania, Romania, and Bulgaria was linked to limited economic resources that hindered full implementation of preventive and treatment programs. Conclusion. The integration of CVD clinical guidelines into the national healthcare systems has played a significant role in reducing mortality. Achieving the full potential of CG implementation requires a comprehensive strategy that ensures access to quality care for the entire population, including preventive and rehabilitation programs, sufficient funding, modern infrastructure, and continuous professional development of healthcare personnel. Systemic integration of guideline-based prevention, diagnostics, and treatment can further reduce CVD morbidity and mortality</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сердечно-сосудистые заболевания</kwd><kwd>смертность</kwd><kwd>клинические рекомендации</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cardiovascular disease</kwd><kwd>mortality</kwd><kwd>clinical guidelines</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Косолапов В.П., Ярмонова М.В. 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