<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">fcmedicine</journal-id><journal-title-group><journal-title xml:lang="ru">Фундаментальная и клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Fundamental and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2500-0764</issn><issn pub-type="epub">2542-0941</issn><publisher><publisher-name>КемГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23946/2500-0764-2025-10-2-105-110</article-id><article-id custom-type="elpub" pub-id-type="custom">fcmedicine-1024</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АНЕСТЕЗИОЛОГИЯ И РЕАНИМАТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANESTHESIOLOGY AND CRITICAL CARE MEDICINE</subject></subj-group></article-categories><title-group><article-title>Особенности искусственного кровообращения при кардиохирургическом вмешательстве у ребенка весом 1,8 кг: клинический случай</article-title><trans-title-group xml:lang="en"><trans-title>Features of cardiopulmonary bypass in cardiac surgery for a child weighing 1.8 kg: a clinical case</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-7717-9856</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зинчук</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zinchuk</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зинчук Полина Вадимовна, младший научный сотрудник лаборатории органопротекции у детей с врожденнымипороками сердца отдела хирургии сердца и сосудов</p><p>д. 6, г. Кемерово, 650002</p></bio><bio xml:lang="en"><p>Dr. Polina V. Zinchuk, MD, Junior Researcher, Laboratory of Organ Protection in Children with Congenital Heart Defects, Department of Cardiovascular Surgery</p><p>Barbarash Boulevard, 6, Kemerovo, 650002</p></bio><email xlink:type="simple">zpv2706@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9479-4694</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балахнин</surname><given-names>Д. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Balakhnin</surname><given-names>D. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Балахнин Дмитрий Геннадьевич, врач-анестезиолог-реаниматолог отделения анестезиологии-реанимации</p><p>ул. Щепкина, д. 61/2, г. Москва, 129110</p></bio><bio xml:lang="en"><p>Dr. Dmitry G. Balakhnin, MD, Anesthesiologist and Emergency Physician, Anesthesiology and Intensive Care Department</p><p>Shchepkina Street, 61/2, Moscow, 129110</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3899-1642</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ивкин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivkin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ивкин Артем Александрович, кандидат медицинских наук, заведующий лабораторией органопротекции у детей с врожденными пороками сердца отдела хирургии сердца и сосудов</p><p>д. 6, г. Кемерово, 650002</p></bio><bio xml:lang="en"><p>Dr. Artem A. Ivkin, MD, Cand. Sci. (Medicine), Head of the Laboratory of Organ Protection in Children with Congenital Heart Defects, Department of Cardiovascular Surgery</p><p>Barbarash Boulevard, 6, Kemerovo, 650002</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний, бульвар имени академика Л.С. Барбараша</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute for Complex Issues of Cardiovascular Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Regional Research and Clinical Institute (MONIKI)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний, бульвар имени&#13;
академика Л.С. Барбараша</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute for Complex Issues of Cardiovascular Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2025</year></pub-date><volume>10</volume><issue>2</issue><fpage>105</fpage><lpage>110</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зинчук П.В., Балахнин Д.Г., Ивкин А.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Зинчук П.В., Балахнин Д.Г., Ивкин А.А.</copyright-holder><copyright-holder xml:lang="en">Zinchuk P.V., Balakhnin D.G., Ivkin A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://fcm.kemsmu.ru/jour/article/view/1024">https://fcm.kemsmu.ru/jour/article/view/1024</self-uri><abstract><p>Цель. Продемонстрировать возможность проведения и безопасность кардиохирургического вмешательства в условиях искусственного кровообращения у ребенка весом 1,8 кг. Материалы и методы. Представлен случай сердечно-сосудистой операции в условиях искусственного кровообращения у ребенка весом 1,8 кг. Результаты. Описаны основные сложности обеспечения анестезиологического пособия и процедуры искусственного кровообращения и пути их преодоления для возможности проведения кардиохирургического вмешательства. Представлены показатели лабораторной и инструментальной диагностики и мониторинга показателей основных жизненных функций в периоперационном периоде, демонстрирующие безопасность проведенных манипуляций для ребенка. Заключение. Достижения современной сердечно-сосудистой хирургии и кардиоанестезиологии предоставляют возможность проведения операций в условиях искусственного кровообращения у недоношенных детей с низкой массой тела. В статье описаны особенности проведения кардиохирургической операции ребенку с массой тела 1,8 кг и доказана её безопасность</p></abstract><trans-abstract xml:lang="en"><p>Aim. To demonstrate the feasibility and safety of performing cardiac surgery under cardiopulmonary bypass (CPB) in a child weighing 1.8 kg. Materials and Methods. We present a case of cardiovascular surgery under CPB in an infant with a body weight of 1.8 kg. Results. The major challenges associated with anesthetic management and CPB procedures are described, along with the strategies employed to overcome them in order to enable successful cardiac surgery. Laboratory and instrumental diagnostic indicators and vital parameters of perioperative monitoring are presented to demonstrate the safety of the procedures performed in this patient. Conclusion. Advances in current cardiovascular surgery and cardiac anesthesiology enable the performance of CPB-assisted operations in premature infants with low body weight. This article outlines the specific features of conducting cardiac surgery in a patient weighing 1.8 kg and provides evidence of its safety</p></trans-abstract><kwd-group xml:lang="ru"><kwd>искусственное кровообращение</kwd><kwd>кардиохирургия</kwd><kwd>недоношенные</kwd><kwd>анестезия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cardiopulmonary bypass</kwd><kwd>cardiac surgery</kwd><kwd>premature infants</kwd><kwd>anaesthesia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Tan C.M.J., Lewandowski A.J. The Transitional Heart: From Early Embryonic and Fetal Development to Neonatal Life. Fetal. Diagn. Ther. 2020;47(5):373–386. https://doi.org/10.1159/000501906</mixed-citation><mixed-citation xml:lang="en">Tan CMJ, Lewandowski AJ. The Transitional Heart: From Early Embryonic and Fetal Development to Neonatal Life. Fetal Diagn Ther. 2020;47(5):373–386. https://doi.org/10.1159/000501906</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Güvener M., Korun O., Demirtürk O.S. Risk factors for systemic inflammatory response after congenital cardiac surgery. J. Card. Surg. 2015;30(1):92–96. https://doi.org/10.1111/jocs.12465</mixed-citation><mixed-citation xml:lang="en">Güvener M, Korun O, Demirtürk OS. Risk factors for systemic inflammatory response after congenital cardiac surgery. J Card Surg. 2015;30(1):92–96. https://doi.org/10.1111/jocs.12465</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Li Y.M., Ran J., Li H., Yan C.Y. [Risk factors for capillary leak syndrome in neonates]. Zhongguo Dang Dai Er Ke Za Zhi. 2011;13(9):708–710. PMID: 21924016</mixed-citation><mixed-citation xml:lang="en">Li YM, Ran J, Li H, Yan CY. [Risk factors for capillary leak syndrome in neonates]. Zhongguo Dang Dai Er Ke Za Zhi. 2011;13(9):708–710. PMID: 21924016</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Chen F., You Y., Ding P., Wu K., Mo X. Effects of Balanced Ultrafiltration During Extracorporeal Circulation for Children with Congenital Heart Disease on Postoperative Serum Inflammatory Response. Fetal. Pediatr. Pathol. 2020;39(5):401–408. https://doi.org/10.1080/15513815.2019.1661050</mixed-citation><mixed-citation xml:lang="en">Chen F, You Y, Ding P, Wu K, Mo X. Effects of Balanced Ultrafiltration During Extracorporeal Circulation for Children with Congenital Heart Disease on Postoperative Serum Inflammatory Response. Fetal Pediatr Pathol. 2020;39(5):401–408. https://doi.org/10.1080/15513815.2019.1661050</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Bierer J., Stanzel R., Henderson M., Sett S., Horne D. Ultrafiltration in Pediatric Cardiac Surgery Review. World J. Pediatr. Congenit. Heart Surg. 2019;10(6):778–788. https://doi.org/10.1177/2150135119870176</mixed-citation><mixed-citation xml:lang="en">Bierer J, Stanzel R, Henderson M, Sett S, Horne D. Ultrafiltration in Pediatric Cardiac Surgery Review. World J Pediatr Congenit Heart Surg. 2019;10(6):778–788. https://doi.org/10.1177/2150135119870176</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Gholampour Dehaki M., Niknam S., Azarfarin R., Bakhshandeh H., Mahdavi M. Zero-Balance Ultrafiltration of Priming Blood Attenuates Procalcitonin and Improves the Respiratory Function in Infants After Cardiopulmonary Bypass: A Randomized Controlled Trial. Artif. Organs. 2019;43(2):167–172. https://doi.org/10.1111/aor.13325</mixed-citation><mixed-citation xml:lang="en">Gholampour Dehaki M, Niknam S, Azarfarin R, Bakhshandeh H, Mahdavi M. Zero-Balance Ultrafiltration of Priming Blood Attenuates Procalcitonin and Improves the Respiratory Function in Infants After Cardiopulmonary Bypass: A Randomized Controlled Trial. Artif Organs. 2019;43(2):167–172. https://doi.org/10.1111/aor.13325</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Holmannova D., Kolackova M., Mandak J., Kunes P., Holubcova Z., Holubec T. et al. Effects of conventional CPB and mini-CPB on neutrophils CD162, CD166 and CD195 expression. Perfusion. 2017;32(2):141–150. https://doi.org/10.1177/0267659116669586</mixed-citation><mixed-citation xml:lang="en">Holmannova D, Kolackova M, Mandak J, Kunes P, Holubcova Z, Holubec T, et al. Krejsek J. Effects of conventional CPB and mini-CPB on neutrophils CD162, CD166 and CD195 expression. Perfusion. 2017;32(2):141–150. https://doi.org/10.1177/0267659116669586</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Delaney M., Stark P.C., Suh M., Triulzi D.J., Hess J.R., Steiner M.E. et al. Massive Transfusion in Cardiac Surgery: The Impact of Blood Component Ratios on Clinical Outcomes and Survival. Anesth. Analg. 2017;124(6):1777–1782. https://doi.org/10.1213/ANE.0000000000001926</mixed-citation><mixed-citation xml:lang="en">Delaney M, Stark PC, Suh M, Triulzi DJ, Hess JR, Steiner ME, et al. Massive Transfusion in Cardiac Surgery: The Impact of Blood Component Ratios on Clinical Outcomes and Survival. Anesth Analg. 2017;124(6):1777–1782. https://doi.org/10.1213/ANE.0000000000001926</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Delaney M., Stark P.C., Suh M., Triulzi D.J., Hess J.R., Steiner M.E. et al. Massive Transfusion in Cardiac Surgery: The Impact of Blood Component Ratios on Clinical Outcomes and Survival. Anesth. Analg. 2017;124(6):1777–1782. https://doi.org/10.1213/ANE.0000000000001926</mixed-citation><mixed-citation xml:lang="en">Delaney M, Stark PC, Suh M, Triulzi DJ, Hess JR, Steiner ME, et al. Massive Transfusion in Cardiac Surgery: The Impact of Blood Component Ratios on Clinical Outcomes and Survival. Anesth Analg. 2017;124(6):1777–1782. https://doi.org/10.1213/ANE.0000000000001926</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Борисенко Д.В., Ивкин А.А., Шукевич Д.Л., Корнелюк Р.А. Значение эритроцитсодержащих компонентов донорской крови в объеме первичного заполнения контура искусственного кровообращения в развитии системного воспаления при коррекции врожденных пороков сердца у детей. Общая реаниматология. 2022;18(3):30–37. https://doi.org/10.15360/1813-9779-2022-3-30-37</mixed-citation><mixed-citation xml:lang="en">Borisenko DV, Ivkin AA, Shukevich DL, Kornelyuk RA. The Effect of Erythrocyte-Containing Donor Blood Components in the Priming of the Cardiopulmonary Bypass Circuit on the Development of Systemic Inflammation During Correction of Congenital Heart Defects in Children. Obshchaya reanimatologiya. 2022;18(3):30–37. (In Russ.). https://doi.org/10.15360/1813-9779-2022-3-30-37</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Burnside J.L., Ratliff T.M., Kelly M.N., Naguib A.N., Galantowicz M., Hodge A. Bloodless Arterial Switch Operation in a 2.7-kg Jehovah's Witness Patient. J. Extra Corpor. Technol. 2020;52(2):142–145. https://doi.org/10.1182/ject-2000003</mixed-citation><mixed-citation xml:lang="en">Burnside JL, Ratliff TM, Kelly MN, Naguib AN, Galantowicz M, Hodge A. Bloodless Arterial Switch Operation in a 2.7-kg Jehovah's Witness Patient. J Extra Corpor Technol. 2020;52(2):142-145. https://doi.org/10.1182/ject-2000003</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
