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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">fcmedicine</journal-id><journal-title-group><journal-title xml:lang="ru">Фундаментальная и клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Fundamental and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2500-0764</issn><issn pub-type="epub">2542-0941</issn><publisher><publisher-name>КемГМУ</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">fcmedicine-120</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ЧЕТВЕРТОЕ УНИВЕРСАЛЬНОЕ ОПРЕДЕЛЕНИЕ ИНФАРКТА МИОКАРДА. ФОКУС НА ИНФАРКТ МИОКАРДА 2-ГО ТИПА</article-title><trans-title-group xml:lang="en"><trans-title>FOURTH UNIVERSAL DEFINITION OF MYOCARDIAL INFARCTION. FOCUS ON THE TYPE 2 MYOCARDIAL INFARCTION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барбараш</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Barbarash</surname><given-names>OLGA L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кашталап</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kashtalap</surname><given-names>VASILIY V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний»; ФГБОУ ВО «Кемеровский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute for Complex Issues of Cardiovascular Diseases; Kemerovo State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2018</year></pub-date><volume>3</volume><issue>4</issue><fpage>73</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Барбараш О.Л., Кашталап В.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Барбараш О.Л., Кашталап В.В.</copyright-holder><copyright-holder xml:lang="en">Barbarash O.L., Kashtalap V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://fcm.kemsmu.ru/jour/article/view/120">https://fcm.kemsmu.ru/jour/article/view/120</self-uri><abstract><p>Представлен обзор истории развития современных представлений о дефиниции диагноза инфаркт миокарда (ИМ), кратко изложены особенности всех редакций международных согласительных документов по универсальному определению ИМ, указано на особую значимость представлений об ИМ 2 типа и описаны клинические сложности, связанные с ведением пациентов с этим диагнозом, обоснована определяющая роль маркеров некроза миокарда (высокочувствительные тропонины) в выявлении ИМ, дано понятие о различиях терминов «инфаркт миокарда» и «повреждение миокарда».</p></abstract><trans-abstract xml:lang="en"><p>Here we review the current concept on the definition of myocardial infarction (MI) and its diagnosis. We briefly highlight features of all international documents on the universal definition of MI and specify type 2 MI as a particularly difficult form. We then consider clinical difficulties in providing medical care to these patients and underline the crucial importance of myocardial necrosis biomarkers (high-sensitivity troponins) in MI diagnosis. Finally, we talk about the principles of distinguishing MI from myocardial injury.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>универсальное определение инфаркта миокарда</kwd><kwd>повреждение миокарда</kwd><kwd>высокочувствительные тропонины</kwd><kwd>инфаркт миокарда 2 типа</kwd><kwd>myocardial infarction</kwd><kwd>myocardial injury</kwd><kwd>high-sensitivity troponins</kwd><kwd>type 2 myocardial infarction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, et al. Fourth universal definition of myocardial infarction (2018). J Am Coll Cardiol. 2018; 72 (18): 2231-2264. doi: 10.1016/j.jacc.2018.08.1038</mixed-citation><mixed-citation xml:lang="en">Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, et al. Fourth universal definition of myocardial infarction (2018). 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