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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">fcmedicine</journal-id><journal-title-group><journal-title xml:lang="ru">Фундаментальная и клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Fundamental and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2500-0764</issn><issn pub-type="epub">2542-0941</issn><publisher><publisher-name>КемГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23946/2500-0764-2020-5-1-64-70</article-id><article-id custom-type="elpub" pub-id-type="custom">fcmedicine-222</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Эпидемиологический надзор за заболеваемостью населения меланомой и другими злокачественными новообразованиями кожи на региональном уровне</article-title><trans-title-group xml:lang="en"><trans-title>Surveillance for melanoma and other skin cancers at the regional level</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0756-2271</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блох</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Blokh</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Блох Алексей Игоревич - ассистент кафедры эпидемиологии, ОГМУ; младший научный сотрудник, ФБУН «ОНИИПОИ.</p><p>644099, Омск, ул. Ленина 12; 644050, Омск, ул. Мира 7</p></bio><bio xml:lang="en"><p>Dr. Alexey I. Blokh - MD, Assistant Professor, Department of Epidemiology, OSMU; Junior Researcher, ORINFI.</p><p>12, Lenina Street, Omsk, 644099; 7, Mira Street, Omsk, 644050</p></bio><email xlink:type="simple">spy_spirit@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3164-8734</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стасенко</surname><given-names>В. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Stasenko</surname><given-names>V. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Стасенко Владимир Леонидович - доктор медицинских наук, профессор, заведующий кафедрой эпидемиологии.</p><p>644099, Омск, ул. Ленина 12</p></bio><bio xml:lang="en"><p>Dr. Vladimir L. Stasenko - MD, DSc, Professor, Head of the Department of Epidemiology.</p><p>12, Lenina Street, Omsk, 644099</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Омский государственный медицинский университет» Министерства здравоохранения Российской Федерации; ФБУН «Омский научно-исследовательский институт природно-очаговых инфекций» Роспотребнадзора</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical University; Omsk Research Institute of Natural Focal Infections</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Омский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>28</day><month>03</month><year>2020</year></pub-date><volume>5</volume><issue>1</issue><fpage>64</fpage><lpage>70</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Блох А.И., Стасенко В.Л., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Блох А.И., Стасенко В.Л.</copyright-holder><copyright-holder xml:lang="en">Blokh A.I., Stasenko V.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://fcm.kemsmu.ru/jour/article/view/222">https://fcm.kemsmu.ru/jour/article/view/222</self-uri><abstract><sec><title>Цель</title><p>Цель. Обоснование предложений по совершенствованию системы эпидемиологического надзора за меланомой и другими злокачественными новообразованиями кожи (ЗНК) на региональном уровне.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Было проведено поперечное исследование распространённости известных факторов риска меланомы и других злокачественных новообразований кожи, в котором приняли участие 1269 жителей Алтайского края старше 18 лет; отклик на исследование составил 84,6% (1269/1500). Для проверки связи между возрастом респондентов (независимая переменная) и посещением ими соляриев (зависимая переменная) была использована простая логистическая регрессия. В качестве меры эпидемиологической значимости факторов риска в конкретной изучаемой популяции был использован дополнительный популяционный риск. Статистическая обработка данных проводилась с использование MS Excel 2010 и Statistica 6.0.</p></sec><sec><title>Результаты</title><p>Результаты. Существующую систему эпидемиологического надзора за заболеваемостью населения меланомой и другими злокачественными новообразованиями кожи необходимо дополнить рутинным сбором информации о распространенности известных факторов риска указанной патологии, среди которых наибольшее значение как управляемый фактор имеет посещение соляриев. Посещение соляриев отметили 7,6% (97/1269) респондентов. При этом шансы обнаружить посещавшего солярий среди молодых были выше (ОШ 0,95; 95% ДИ 0,93 ÷ 0,97 на дополнительный год, р&lt;0,0001), что вызывает особые опасения и может свидетельствовать о росте активности данного фактора в популяции. За счёт исключения немедицинского посещения соляриев населением Алтайского края ежегодно может быть предотвращено до 6,2% случаев меланомы и 2,95%-7,19% случаев других ЗНК, что согласуется с мировыми данными. Наиболее восприимчивые к воздействию ультрафиолетового излучения фототипы кожи (I и II по Fitzpatrick) среди респондентов имели 11,5% (146/1266) и 29,8% (377/1266) соответственно.</p></sec><sec><title>Заключение</title><p>Заключение. Таким образом, рутинное отслеживание приведённых выше детерминант и факторов риска заболеваемости населения меланомой и другими ЗНК может способствовать улучшению профилактической помощи населению. Так, распространённость наиболее ассоциированных с риском развития меланомы и других ЗНК фототипов кожи (I и II по Fitzpatrick) составила около 40%. Наиболее значимый управляемый фактор риска - посещение соляриев - отмечен только 7,6% респондентов. Дополнительный популяционный риск развития меланомы и других ЗНК, связанный с посещением соляриев, составил 6,2% и 2,95%-7,19% для меланомы и других ЗНК соответственно.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To justify the proposals for improving the surveillance for melanoma and non-melanoma skin cancers at the regional level.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods. We conducted a cross-sectional study investigating the prevalence of known risk factors for melanoma and non-melanoma skin cancers. In total, 1269 residents of the Altai Krai ≥ 18 years were the study participants; the response rate was 84.6% (1269/1500). Logistic regression was used to test the relationship between the age of the respondents (independent variable) and their visits to the tanning salons (dependent variable). The population attributable risk was used to measure the epidemiological significance of the risk factors in a specific study population.</p></sec><sec><title>Results</title><p>Results. The current system of epidemiological surveillance for melanoma and non-melanoma skin cancers needs to be supplemented with a routine data collection on the prevalence of known risk factors, among which visiting of the tanning salons has particular importance as a controllable factor which was present in 7.6% (97/1269) respondents. Identification rate regarding this risk factor was higher among the young people (OR 0.95; 95% CI 0.93 ÷ 0.97 per an additional year, p &lt;0.0001). Up to 6.2% of melanoma cases and 2.95-7.19% of non-melanoma skin cancers among the population of Altai Krai could be prevented annually by the exclusion of non-medical visits to the tanning salons. The most ultraviolet-susceptible phototypes of the skin (Fitzpatrick I and II) were present in 11.5% (146/1266) and 29.8% (377/1266) of respondents, respectively.</p></sec><sec><title>Conclusion</title><p>Conclusion. Routine assessment of the risk factors of melanoma and non-melanoma skin cancers can contribute to the efficient surveillance and prevention. Total prevalence of skin phototypes most associated with the risk of developing melanoma and non-melanoma skin cancers (Fitzpatrick I and II) was about 40%. The most significant controllable risk factor, i.e. visiting tanning salons, was noted only by 7.6% of respondents. The population attributable risk of developing melanoma and non-melanoma skin cancers associated with visiting tanning salons was 6.2% and 2.95-7.19% for melanoma and non-melanoma skin cancers respectively.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>злокачественные новообразования кожи</kwd><kwd>меланома кожи</kwd><kwd>дополнительный популяционный риск</kwd><kwd>эпидемиологический надзор</kwd><kwd>фактор риска</kwd><kwd>Алтайский край</kwd></kwd-group><kwd-group xml:lang="en"><kwd>skin cancer</kwd><kwd>melanoma</kwd><kwd>population attributable risk</kwd><kwd>surveillance</kwd><kwd>risk factor</kwd><kwd>Altaikrai</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bray F, Colombet M, Mery L, Pineros M, Znaor A, Zanetti R, Ferlay J, editors. Cancer Incidence in Five Continents, Vol. XI (electronic version). Lyon: International Agency for Research on Cancer. 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