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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">fcmedicine</journal-id><journal-title-group><journal-title xml:lang="ru">Фундаментальная и клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Fundamental and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2500-0764</issn><issn pub-type="epub">2542-0941</issn><publisher><publisher-name>КемГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23946/2500-0764-2024-9-1-25-32</article-id><article-id custom-type="elpub" pub-id-type="custom">fcmedicine-822</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Масса тела новорожденного в современной популяции свердловской области (результаты пилотного исследования)</article-title><trans-title-group xml:lang="en"><trans-title>Assessment of Birth Weight Parameters in Sverdlovsk Region: Preliminary Results</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4031-4907</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беломестнов</surname><given-names>С. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Belomestnov</surname><given-names>S. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Беломестнов Сергей Разумович, кандидат медицинских наук, доцент кафедры акушерства и гинекологии, трансфузиологии</p><p>620028, г. Екатеринбург, ул. Репина, д. 3</p></bio><bio xml:lang="en"><p>Dr. Sergey R. Belomestnov, MD, PhD, Associate Professor, Department of Obstetrics, Gynecology and Transfusiology</p><p>3, Repina Street, Yekaterinburg, 620028 </p></bio><email xlink:type="simple">beldoctor@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7965-2364</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чумарная</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Сhumarnaya</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чумарная Татьяна Владиславовна, кандидат биологических наук, старший научный сотрудник лаборатории математической физиологии им. В. С. Мархасина</p><p>620049, г. Екатеринбург, ул. Первомайская, д. 106 </p></bio><bio xml:lang="en"><p>Mrs. Tatiana V. Сhumarnaya, PhD, Senior Researcher, Laboratory for Mathematical Physiology</p><p>106, Pervomaiskaya Street, Yekaterinburg, 620049, </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0828-0479</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Севостьянова</surname><given-names>О. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Sevostyanova</surname><given-names>O. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Севостьянова Ольга Юрьевна, доктор медицинских наук, профессор кафедры акушерства и гинекологии</p><p>620028, г. Екатеринбург, ул. Репина, д. 3</p></bio><bio xml:lang="en"><p>Prof. Olga Yu. Sevostyanova, MD, DSc, Professor, Department of Obstetrics and Gynecology</p><p>3, Repina Street, Ekaterinburg, 620028 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-3432-9334</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ксенофонтов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ksenofontov</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ксенофонтов Алексей Михайлович, врач акушер-гинеколог </p><p>620066, г. Екатеринбург, ул. Комсомольская, д. 9</p></bio><bio xml:lang="en"><p>Dr. Alexey M. Ksenofontov, MD, Obstetrician-Gynecologis </p><p>9, Komsomolskaya Street, Ekaterinburg, 620066 </p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9935-4372</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анкудинов</surname><given-names>Н. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Аnkudinov</surname><given-names>N. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анкудинов Николай Олегович, руководитель акушерского дистанционного консультативного центра</p><p>620066, г. Екатеринбург, ул. Комсомольская, д. 9</p></bio><bio xml:lang="en"><p>Dr. Nikolay O. Аnkudinov , Head of the Obstetric Remote Consultation Centre</p><p>9, Komsomolskaya Street, Ekaterinburg, 620066 </p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0050-9301</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исакова</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Isakova</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Исакова Татьяна Михайловна, кандидат медицинских наук, доцент кафедры онкологии и лучевой диагностики</p><p>620028, г. Екатеринбург, ул. Репина, д. 3</p></bio><bio xml:lang="en"><p>Dr. Tatiana M. Isakova, MD, PhD, Associate Professor</p><p>3, Repina Street, Ekaterinburg, 620028 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Уральский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Urals State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУН «Институт иммунологии и физиологии Уральского отделения Российской академии наук»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ Свердловской области «Екатеринбургский клинический перинатальный центр»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yekaterinburg Clinical Perinatal Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>29</day><month>03</month><year>2024</year></pub-date><volume>9</volume><issue>1</issue><fpage>25</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Беломестнов С.Р., Чумарная Т.В., Севостьянова О.Ю., Ксенофонтов А.М., Анкудинов Н.О., Исакова Т.М., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Беломестнов С.Р., Чумарная Т.В., Севостьянова О.Ю., Ксенофонтов А.М., Анкудинов Н.О., Исакова Т.М.</copyright-holder><copyright-holder xml:lang="en">Belomestnov S.R., Сhumarnaya T.V., Sevostyanova O.Y., Ksenofontov A.M., Аnkudinov N.O., Isakova T.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://fcm.kemsmu.ru/jour/article/view/822">https://fcm.kemsmu.ru/jour/article/view/822</self-uri><abstract><sec><title>Цель</title><p>Цель. Определение процентильных границ массы тела доношенного новорожденного для современного населения Свердловской области и сравнение их с результатами популяционного исследования, проведенного в Центральной Европе.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен ретроспективный анализ данных 41745 женщин. Критерии включения: одноплодная доношенная беременность; отсутствие пороков развития плода; родоразрешение в лицензированной медицинской организации. Критерии исключения: многоплодная беременность, наличие признаков хромосомных аномалий при оценке антенатального развития плода, врожденные пороки развития ребенка, незавершенное обследование по стандарту, применяемому для нормальной беременности. Полученные результаты сравнивались с аналогичным исследованием, осуществлённым в Центральной Европе. Числовые показатели проанализированы непараметрическими методами статистики, использован процентильный подход. Различия количественных показателей подтверждались при помощи U-критерия Манна-Уитни. Статистически значимыми считали различия при уровне p&lt;0,05.</p></sec><sec><title>Результаты</title><p>Результаты. Медианное значение веса (гр.)новорожденных (Ме – 50-й процентиль) в сроке 37 нед. составило 3010, 38 нед. – 3180, 39 нед. – 3350, 40 нед. – 3490, 41 нед. – 3600. Критерий «большой для гестационного возраста» (90-й процентиль) в сроке 37 нед. – 3550, 38 нед. – 3720, 39 нед. – 3900, 40 нед. – 4020, 41 нед. – 4150 гр. Выявлено достоверное повышение медианного значения веса новорожденных центральноевропейской популяции (Ме – 50-й процентиль) относительно детей современной популяции Свердловской области во всех гестационных возрастах (р&lt;0,05).</p></sec><sec><title>Заключение</title><p>Заключение. Старший репродуктивный возраст и паритет являются существенными популяционными факторами, определяющими характеристики новорожденных. Одной из причин, способствующих реализации этих факторов, являются метаболические нарушения. Масса тела новорожденного в современной популяции Свердловской области отличается от этого параметра в центральноевропейской популяции, что требует проведения дальнейших исследований. Использование полученных данных способствует корректной оценке новорожденного с учетом региональных критериев и разработке территориальной стратегии профилактики нарушений роста плода.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To define median and large-for-gestational-age birth weight in Sverdlovsk Region and to compare them with the results of a population study conducted in Central Europe.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods. We conducted a retrospective analysis of 41,745 women. Inclusion criteria were singleton, full-term pregnancy, absence of fetal malformations, and delivery in a licensed medical organization. Exclusion criteria were multiple pregnancy, signs of chromosomal abnormalities during the antenatal development, congenital malformations, and incomplete examination according to the standard used for normal pregnancy. The results were compared with a similar study carried out in Central Europe.</p></sec><sec><title>Results</title><p>Results. The median weight of newborns at 37, 38, 39, 40, and 41 weeks was 3010, 3180, 3350, 3490, and 3600 g, respectively. “Large for gestational age” (above the 90th percentile) weight at 37, 38, 39, 40, and 41 weeks was 3550, 3720, 3900, 4020, and 4150 g, respectively. These parameters were significantly lower than those in Central Europe. Reproductive age, parity, and metabolic disorders were significant population determinants of birth weight.</p></sec><sec><title>Conclusion</title><p>Conclusion. Birth weight parameters in Sverdlovsk Region differ from those in Central Europe, requiring further research. These data might be used for the correct assessment of the newborns and for development of a territorial strategy for the prevention of fetal growth disorders.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>рост плода</kwd><kwd>большой для гестационного возраста</kwd><kwd>вес при рождении</kwd><kwd>новорожденный</kwd></kwd-group><kwd-group xml:lang="en"><kwd>fetal height</kwd><kwd>large for gestational age</kwd><kwd>birth weight</kwd><kwd>newborn</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Железнов Л.М., Никифорова С.А., Леванова О.А. Особенности региональных показателей фетометрии для анатомических исследований. Wschodnioeuropejskie czasopismo naukowe. 2016;8(2):44-47.</mixed-citation><mixed-citation xml:lang="en">Jeleznov LM, Nikiforova SA, Levanova OA. Features regional indicators fetometry for anatomical studies. 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