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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">fcmedicine</journal-id><journal-title-group><journal-title xml:lang="ru">Фундаментальная и клиническая медицина</journal-title><trans-title-group xml:lang="en"><trans-title>Fundamental and Clinical Medicine</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2500-0764</issn><issn pub-type="epub">2542-0941</issn><publisher><publisher-name>КемГМУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.23946/2500-0764-2024-9-2-86-93</article-id><article-id custom-type="elpub" pub-id-type="custom">fcmedicine-866</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLES</subject></subj-group></article-categories><title-group><article-title>Плацентарные нарушения как фактор риска развития послеродового кровотечения</article-title><trans-title-group xml:lang="en"><trans-title>Placental Disorders as a Risk Factor for the Development of Postpartum Haemorrhage</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5447-4223</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белокриницкая</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Belokrinitskaya</surname><given-names>T. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Белокриницкая Татьяна Евгеньевна, доктор медицинских наук, профессор, заведующая кафедрой акушерства и гинекологии педиатрического факультета и факультета дополнительного профессионального образования</p><p>672000, г. Чита, ул. Горького, д. 39а</p></bio><bio xml:lang="en"><p>Prof. Tatiana Е. Belokrinitskaya, MD, DSc, Professor, Chief of the Department of Obstetrics and Gynecology, Pediatric Faculty and Faculty of Professional Retraining</p><p>39a, Gor’kogo Street, Chita, 672000 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4509-0698</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сидоркина</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Sidorkina</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сидоркина Анастасия Геннадьевна, ассистент кафедры акушерства и гинекологии педиатрического факультета и факультета дополнительного профессионального образования</p><p>672000, г. Чита, ул. Горького, д. 39а</p></bio><bio xml:lang="en"><p>Dr. Anastasia G. Sidorkina, MD, Assistant Professor, Department of Obstetrics and Gynecology, Pediatric Faculty and Faculty of Professional Retraining</p><p>39a, Gor’kogo Street, Chita, 672000 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5961-5400</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мудров</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mudrov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мудров Виктор Андреевич, доктор медицинских наук, доцент кафедры акушерства и гинекологии педиатрического факультета и факультета дополнительного профессионального образования</p><p>672000, г. Чита, ул. Горького, д. 39а</p></bio><bio xml:lang="en"><p>Dr. Viktor A. Mudrov, MD, DSc, Associate Professor, Chief of the Department of Obstetrics and Gynecology, Pediatric Faculty and Faculty of Professional Retraining</p><p>39a, Gor’kogo Street, Chita, 672000</p></bio><email xlink:type="simple">mudrov_viktor@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Читинская государственная медицинская академия» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Chita State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>21</day><month>06</month><year>2024</year></pub-date><volume>9</volume><issue>2</issue><fpage>86</fpage><lpage>93</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Белокриницкая Т.Е., Сидоркина А.Г., Мудров В.А., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Белокриницкая Т.Е., Сидоркина А.Г., Мудров В.А.</copyright-holder><copyright-holder xml:lang="en">Belokrinitskaya T.E., Sidorkina A.G., Mudrov V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://fcm.kemsmu.ru/jour/article/view/866">https://fcm.kemsmu.ru/jour/article/view/866</self-uri><abstract><p>Плацента является функциональным звеном между матерью и плодом во время беременности и важнейшим фактором, определяющим не только состояние новорожденного, но и здоровье человека на протяжении всей последующей жизни. Цель исследования - анализ литературы по теме плацентарные нарушения в качестве фактора риска развития послеродовых кровотечений. В ходе исследования проведен детальный систематический анализ современной отечественной и зарубежной литературы, посвященной плацентарным нарушениям и послеродовым кровотечениям. В исследовании использовались такие информационные базы, как: PubMed, PubMed Central, Scopus, MEDLINE, ScienceDirect, Cochrane Library, eLibrary за период с 2001 г. до октября 2023 г. При плацентарной недостаточности могут развиваться две компенсаторные реакции со стороны плаценты. Первая реакция – гиперплазия плаценты. При этом состоянии плацента увеличивается в объёме, чтобы удовлетворять все потребности в питательных веществах у растущего плода. Вторая реакция – гипоплазия плаценты. При небольших размерах плаценты у плода, который испытывает дефицит питательных веществ и кислорода, замедляются рост и развитие, чтобы соответствовать функциональным возможностям плаценты. Но есть ли взаимосвязь между хронической плацентарной недостаточностью и послеродовым кровотечением? Послеродовое кровотечение является основной причиной материнской заболеваемости и смертности во всем мире. На развитие послеродового кровотечения влияет множество факторов, в том числе и размеры плацентарной площадки.</p></abstract><trans-abstract xml:lang="en"><p>The placenta is a functional link between mother and fetus during pregnancy and the most important factor determining newborn and infant health. Postpartum hemorrhage is a leading cause of maternal morbidity and mortality worldwide and is affected by numerous factors including placental size. Here we analysed the role of placental disorders as a risk factor for the development of postpartum hemorrhage. We screened the available literature via PubMed, PubMed Central, Scopus, MEDLINE, ScienceDirect, Cochrane Library, and eLibrary from 2001 to October 2023. Placental insufficiency may cause either hyperplasia (i.e., placental expansion to meet the nutritional needs of the growing fetus) or hypoplasia, which cause deficiency in nutrients and oxygen and slows down fetal growth and development. Both of these conditions significantly affect the probability and volume of postpartum haemorrhage.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>плацентарная недостаточность</kwd><kwd>задержка роста плода</kwd><kwd>преэклампсия</kwd><kwd>послеродовое кровотечение</kwd><kwd>гипотония матки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>placental insufficiency</kwd><kwd>fetal growth restriction</kwd><kwd>pre-eclampsia</kwd><kwd>postpartum hemorrhage</kwd><kwd>uterine hypotension</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Colson A., Sonveaux P., Debieve F., Sferruzzi-Perri A.N. 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