fcmedicineФундаментальная и клиническая медицинаFundamental and Clinical Medicine2500-07642542-0941КемГМУ10.23946/2500-0764-2025-10-1-75-86fcmedicine-973Research ArticleВНУТРЕННИЕ БОЛЕЗНИINTERNAL MEDICINEКачество жизни пациентов при терминальной хронической болезни почек с саркопениейQuality of life in patients with end-stage chronic kidney disease and sarcopeniahttps://orcid.org/0000-0002-2000-3562УткинаЕ. В.UtkinaE. V.

Уткина Екатерина Владимировна, ассистент, аспирант кафедры факультетской терапии и профпатологии имени профессора В.В. Сырнева

ул. Ворошилова, 22а, Кемерово, 650056

Dr. Ekaterina V. Utkina И, MD, Assistant Professor, Postgraduate Student, Department of Clinical Therapy and Occupational Pathology

ул. Ворошилова, 22а, Кемерово, 650056

goll1997.2011@mail.ruhttps://orcid.org/0000-0003-2139-5446ФоминаН. В.FominaN. V.

Фомина Наталья Викторовна, доктор медицинских наук, доцент, заведующий кафедрой факультетской терапии и профпатологии имени профессора В.В. Сырнева федерального государственного бюджетного образовательного учреждения высшего образования «Кемеровский государственный медицинский университет» Министерства здравоохранения Российской Федерации

ул. Ворошилова, 22а, Кемерово, 650056,

Октябрьский проспект, д.22, Кемерово, 650066

Dr. Natalia V. Fomina, MD, Dr. Sci. (Medicine), Head of the Department of Clinical Therapy and Occupational Pathology, Kemerovo State Medical University

ул. Ворошилова, 22а, Кемерово, 650056, 

Oktyabrskiy Prospekt, 22, Kemerovo, 650066

https://orcid.org/0009-0009-0762-4493КириленкоС. В.KirilenkoS. V.

Кириленко Сергей Владимирович, заведующий отделением, врач-нефролог

Советский проспект 38, Кемерово, 650000

Dr. Sergey V. Kirilenko, MD, Head of the Nephrological Unit

Sovetskiy Prospekt, 38, Kemerovo, 650000

Кемеровский государственный медицинский университетРоссияKemerovo State Medical UniversityRussian FederationКемеровский государственный медицинский университет; Кузбасская областная клиническая больница имени С. В. БеляеваРоссияKemerovo State Medical University; Belyaev Kuzbass Regional Clinical HospitalRussian FederationООО «НефроМед»РоссияNefroMed LLCRussian Federation2025260320251017586Copyright © Уткина Е.В., Фомина Н.В., Кириленко С.В., 20252025Уткина Е.В., Фомина Н.В., Кириленко С.В.Utkina E.V., Fomina N.V., Kirilenko S.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://fcm.kemsmu.ru/jour/article/view/973

Цель. Выявить взаимосвязи между показателями качества жизни и диагностическими критериями саркопении у пациентов с терминальной почечной недостаточностью. Материалы и методы. В исследование включено 182 пациента с ХБП С5, проживающих в Кемеровской области. Саркопения была диагностирована у 56 пациентов в соответствии с диагностическими критериями (мышечная масса, мышечная сила, мышечная функция (физическая работоспособность), предложенными Европейской рабочей группой по саркопении у пожилых людей (The European Working Group on Sarcopenia in Older People 2, EWGSOP2). Для оценки КЖ были использованы специфический для диализных пациентов опросник KDQOL-SF™, версия 1.3 (Kidney Disease Quality of Life Short Form, v. 1.3) и опросник SarQoL (Sarcopeni-Quality of Life), рекомендованный для людей пожилого возраста с саркопенией. Результаты. У пациентов с саркопенией и ХБП С5 в опроснике KDQOLSF ™ по специфическим шкалам отмечались низкие значения по следующим шкалам: обременённость ХБП – 60 [53,75; 70,0], когнитивные функции – 61,1 [50,0; 66,67], качество социального взаимодействия – 66,67 [55,56; 73,61], качество сна – 60,71 [57,14; 64,29] и общей шкалы – общее восприятие здоровья 60 [50; 60]. При анализе опросника SarQoL определены низкие показатели КЖ пациентов с ХБП и саркопенией на ГД по следующим доменам: физическое и психическое здоровье 61 [54; 71] балла, передвижение – 68 [65; 68] балла, состав тела – 45 [30; 45] балла, досуг – 50 [50; 50] балла. Выявлена прямая коррелляционная связь средней силы между краткой батареей тестов физического функционирования (SPPB) и следующими доменами: повседневная деятельность (r = 0,66, p < 0,05), функциональность (r = 0,72, p < 0,05), состав тела (r = 0,65), физическое и психическое здоровье (r = 0,66, p < 0,05). Заключение. Выявлены взаимосвязи между SPPB с тремя специфическими шкалами опросника KDQOL-SF™ (симптомы/проблемы, когнитивные функции, качество социального взаимодействия) и пятью доменами опросника SarQoL (досуг, повседневная деятельность, функциональность, состав тела, физическое и психическое здоровье).

Aim. To perform a correlation analysis between QoL scales and diagnostic indicators of sarcopenia in CKD stage 5 (CKD5) patients, determined using bioimpedance spectroscopy (BIS) for body composition assessment. Materials and Methods. The study included 182 CKD5 patients residing in the Kemerovo Region. Sarcopenia was diagnosed in 56 patients according to the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria. To assess QoL, we applied a dialysis-specific Kidney Disease Quality of Life Short Form ((KDQOL-SF) version 1.3 and sarcopenia-specific Sarcopenia Quality of Life (SarQoL) questionnaires. Results. In patients with sarcopenia and CKD5, the KDQOL-SF questionnaire showed low scores with regards to the following specific scales: CKD burden (60 [53.75; 70.0]), cognitive functions (61.1 [50.0; 66.67]), quality of social interaction (66.67 [55.56; 73.61]), quality of sleep (60.71 [57.14; 64.29]) and general perception of health (60 [50; 60]). The SarQoL questionnaire demonstrated low QoL scores in the following domains: physical and mental health (61 [54; 71]), locomotion (68 [65; 68]), body composition (45 [30; 45]), leisure activities (50 [50; 50]). A moderate and statistically significant positive correlation was identified between the Short Physical Performance Battery (SPPB) and the following domains: daily activities (r = 0.66), functionality (r = 0.72), body composition (r = 0.65), and physical and mental health (r = 0.66). Conclusion. Correlations were identified between SPPB scores and three specific scales of the KDQOL-SF questionnaire (symptoms/problems, cognitive function, and quality of social interaction), as well as five domains of the SarQoL questionnaire (leisure activities, activities of daily living, functionality, body composition, physical and mental health).

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The authors declare that there are no conflicts of interest present.