Evaluation of the effectiveness of fetal heart rate analysis using phonocardiography with novel mathematical methods of audiogram processing
https://doi.org/10.23946/2500-0764-2025-10-3-47-60
Abstract
Aim. To evaluate the sensitivity and specificity of a phonocardiography-based method for diagnosing fetal hypoxia using the FetaCare software and hardware complex. Materials and Methods. The study included 204 pregnant women with a high degree of perinatal risk who were stratified into three groups by gestational age: 1) 26–31.6 weeks; 2) 32–36.6 weeks; 3) 37–41 weeks. Phonocardiography records of the fetus were obtained for all participants, followed by mathematical audio data processing and construction of cardiointervalograms. Fetal condition was assessed based on cardiointervalogram-derived parameters: basal fetal heart rate, oscillation amplitude, number of oscillations, acceleration amplitude, number of accelerations, long-term variation, and short-term variation. Sensitivity and specificity of the method was calculated based on short-term variation and long-term variation. Results. Depending on the gestational age group, sensitivity ranged from 40 % to 100 %, while specificity ranged from 95% to 100 %. Conclusion. Diagnostic accuracy of a phonocardiography- and audiogram processing-based heart rate analysis increased with gestational age. Before 32 weeks, it accuracy remained low, requiring the use of additional fetal examination methods to make a decision on the need for delivery. This study demonstrates that the informativeness of phonocardiography with novel audio data processing methods can be comparable to cardiotocography, which is currently widely used in clinical practice.
Keywords
Supporting agencies: The research was granted by the Russian Science Foundation № 24-64-00006, http://rscf.ru/project/24-64-00006/
About the Authors
E. S. Repina
Siberian State Medical University
Russian Federation
Russian Federation
Dr. Ekaterina S. Repina, MD, Assistant Professor, Department of Obstetrics and Gynecology
Moskovskiy Trakt, 2, Tomsk, 634050
S. Yu. Yuriev
Siberian State Medical University; Perinatal Health Center, LLC
Russian Federation
Russian Federation
Prof. Sergey Yu. Yuriev, MD, Dr. Sci. (Medicine), Professor, Department of Obstetrics and Gynecology; Chief Executive Officer
Moskovskiy Trakt, 2, Tomsk, 634050
Sibirskaya Street, 9/1, Tomsk, 634029
Ya. V. Kosteley
Tomsk State University of Control Systems and Radioelectronics; Diagnostika +, LLC
Russian Federation
Russian Federation
Dr. Yana V. Kosteley, Cand. Sci. (Engineering), Associate Professor, Department of Economic Mathematics, Computer Science and Statistics; Software Engineer
Lenina Avenue, 40, Tomsk, 634050
Frunze Avenue, 11b, Tomsk, 634029
N. D. Zimina
Siberian State Medical University
Russian Federation
Russian Federation
Ms. Natalia D. Zimina, MD, Technical Assistant, the Multidisciplinary Accreditation and Simulation Center
Moskovskiy Trakt, 2, Tomsk, 634050
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For citations:
Repina E.S., Yuriev S.Yu., Kosteley Ya.V., Zimina N.D. Evaluation of the effectiveness of fetal heart rate analysis using phonocardiography with novel mathematical methods of audiogram processing. Fundamental and Clinical Medicine. 2025;10(3):47-60. (In Russ.) https://doi.org/10.23946/2500-0764-2025-10-3-47-60
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