Prostate cancer: morbidity and mortality trends in Kemerovo Region
https://doi.org/10.23946/2500-0764-2020-5-1-87-92
Abstract
Aim. To study current trends in the incidence and mortality of prostate cancer in Kemerovo Region.
Materials and Methods. We conducted a descriptive retrospective study by investigating cancer registry of Regional Clinical Oncology Dispensary collected in 2010-2018.
Results. During the study period, 4965 cases of prostate cancer have been documented. The average standardised incidence rate was 50,080/0000 (95% CI = 46.01; 54.43). We detected a trend towards an increase in standardized incidence from 32.410/0000 in 2010 (95% CI = 28.76; 36.05) to 73.000/0000 in 2018 (95% CI = 67.86 – 78.15) with the average annual increment of 10.22% (р < 0.0001). A significant proportion of cases (48.17% in 2018) occurred in elderly (≥ 70 years). Standardized mortality rates increased from 9.240/0000 in 2010 (95% CI = 7.29; 11.19) to 28,830/0000 in 2018 (95% CI = 25.51; 32.15), average annual increment 13.99% (р = 0.002). Component analysis showed that an incidence increase by 155.81% is primarily associated with existing risk factors (128.19%) rather than with population aging (16.71%) or their combined effect (10.91%).
Conclusion. Currently, there is a clear trend to increasing incidence and mortality from prostate cancer in Kemerovo Region, mainly due to existing risk factors.
About the Authors
A. V. Smirnov,
Kemerovo State Medical University
Russian Federation
Russian Federation
Dr. Alexey V. Smirnov - MD, PhD Student, Department of Epidemiology
22a, Voroshilova Street, Kemerovo, 650056, Russian Federation
Yu. A. Magarill
Kemerovo State Medical University
Russian Federation
Russian Federation
Dr. Yuriy A. Magarill - MD, PhD, Head of the Department of Diagnostic Radiology, Radiotherapy and Oncology.
22a, Voroshilova Street, Kemerovo, 650056, Russian Federation
T. A. Shternis
Kemerovo State Medical University
Russian Federation
Russian Federation
Dr. Tatiana A. Shternis - MD, PhD, Associate Professor, Department of Public Health and Medical Informatics.
22a, Voroshilova Street, Kemerovo, 650056, Russian Federation
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Review
For citations:
Smirnov, A.V., Magarill Yu.A., Shternis T.A. Prostate cancer: morbidity and mortality trends in Kemerovo Region. Fundamental and Clinical Medicine. 2020;5(2):87-92. (In Russ.) https://doi.org/10.23946/2500-0764-2020-5-1-87-92
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