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COMPARISON OF RADIAL ARM MAZE ANDMORRIS WATER MAZE FOR EVALUATION OFSPATIAL MEMORY IN EXPERIMENTAL ANIMALS DURING NEUROBEHAVIORAL TESTING

Abstract

Rodents are widely used for the evaluation of the spatial memory due to inherited predisposition and relatively easy training. A number of mazes have been successfully developed and used, with Morris water maze and eight-arm radial maze being two the most appropriate. In this review, we compare advantages and shortcomings of these two tests.

About the Authors

ALEKSANDR M. Iptyshev
Krasnoyarsk State Medical University
Russian Federation


YANA V. Gorina
Krasnoyarsk State Medical University
Russian Federation


OLGA L. Lopatina
Research Institute of Molecular Medicine and Pathological Biochemistry
Russian Federation


YULIYA K. Komleva
Research Institute of Molecular Medicine and Pathological Biochemistry
Russian Federation


ANATOLIY I. Chernykh
Krasnoyarsk City Hospital №20
Russian Federation


OLGA A. Belova
Krasnoyarsk State Medical University
Russian Federation


ALLA B. Salmina
Research Institute of Molecular Medicine and Pathological Biochemistry
Russian Federation


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Review

For citations:


Iptyshev A.M., Gorina Ya.V., Lopatina O.L., Komleva Yu.K., Chernykh A.I., Belova O.A., Salmina A.B. COMPARISON OF RADIAL ARM MAZE ANDMORRIS WATER MAZE FOR EVALUATION OFSPATIAL MEMORY IN EXPERIMENTAL ANIMALS DURING NEUROBEHAVIORAL TESTING. Fundamental and Clinical Medicine. 2017;2(2):62-69. (In Russ.)

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