Поражения кожи у медицинских работников в период пандемии СOVID-19, ассоциированные со средствами индивидуальной защиты
Аннотация
Цель. Обзор результатов опубликованных исследований поражений кожи у медицинских работников, обусловленных средствами индивидуальной защиты.
Материал и методы. Выполнен обзор исследований, опубликованных в базах данных PubMed, OVID, EMBASE, MEDLINE, Google Scholar, eLIBRARY, UpToDate. Изученные статьи написаны на русском и английском языках и опубликованы с 1 января 2020-го по октябрь 2021 года. Для поиска использовались ключевые слова «медицинские работники», «кожа», «дерматозы», «профессиональный», «PPE» в сочетании со словами «COVID-19» и «SARSCoV-2».
Результаты. Контактный дерматит составляет 90% всех случаев заболеваний кожи, причем 20% всех случаев этой патологии приходятся на профессиональный контактный дерматит. В период пандемии COVID-19 в результате продолжительного ношения СИЗ, частого мытья и обработки рук, по разным данным, от 42,8% до 97% медицинских работников сообщили о поражениях кожи в результате повреждающего действия средств индивидуальной защиты. Среди них 61,7% отметили ухудшение ранее существовавшего заболевания кожи, а 90,5% сообщили о появлении новых симптомов поражения кожи, связанных с использованием СИЗ. В числе самых распространенных симптомов поражений кожи у медицинских работников ‒ сухость, зуд, жжение, болезненность кожи и появление на ней высыпаний. Чаще всего у опрошенных медицинских работников регистрировались простой раздражительный и аллергический контактный дерматит, акне, розацеа, себорейный дерматит. Развитие СИЗ-ассоциированных дерматозов зависело от типа СИЗ, материала, из которого они изготовлены, продолжительности использования, наличия кожных заболеваний в анамнезе.
Заключение. Профессиональные дерматозы, связанные с использованием СИЗ, широко распространены среди медицинских работников по всему миру. Это свидетельствует о необходимости поиска новых материалов и средств защиты медицинских работников, правил применения, минимизирующих риск развития СИЗ-ассоциированных поражений кожи.
Об авторе
Н. И. ГалимоваРоссия
Галимова Ника Игоревна, ассистент кафедры эпидемиологии, инфекционных болезней и дерматовенерологии
650056, г. Кемерово, ул. Ворошилова, д. 22а
Список литературы
1. Abdali S, Yu J. Occupational Dermatoses Related to Personal Protective Equipment Used During the COVID-19 Pandemic. Dermatol Clin. 2021;39(4):555-568. https://doi.org/10.1016/j.det.2021.05.009
2. Battista RA, Ferraro M, Piccioni LO, Malzanni GE, Bussi M. Personal Protective Equipment (PPE) in COVID 19 Pandemic: Related Symptoms and Adverse Reactions in Healthcare Workers and General Population. J Occup Environ Med. 2021;63(2):e80-e85. https://doi.org/10.1097/JOM.0000000000002100
3. Jiang Q, Song S, Zhou J, Liu Y, Chen A, Bai Y, Wang J, Jiang Z, Zhang Y, Liu H, Hua J, Guo J, Han Q, Tang Y, Xue J. The Prevalence, Characteristics, and Prevention Status of Skin Injury Caused by Personal Protective Equipment Among Medical Staff in Fighting COVID-19: A Multicenter, Cross-Sectional Study. Adv Wound Care (New Rochelle). 2020;9(7):357-364. https://doi.org/10.1089/wound.2020.1212
4. Balato A, Ayala F, Bruze M, Crepy MN, Gonçalo M, Johansen J, John SM, Pigatto P, Raimondo A, Rustemeyer T, Schuttelaar MA, Svedman C, Aerts O, Uter W, Wilkinson M, Gimenez-Arnau A. European Task Force on Contact Dermatitis statement on coronavirus disease-19 (COVID-19) outbreak and the risk of adverse cutaneous reactions. J Eur Acad Dermatol Venereol. 2020;34(8):e353-e354. https://doi.org/10.1111/jdv.16557
5. Akl J, El-Kehdy J, Salloum A, Benedetto A, Karam P. Skin disorders associated with the COVID-19 pandemic: A review. J Cosmet Dermatol. 2021;20(10):3105-3115. https://doi.org/10.1111/jocd.14266
6. Patruno C, Fabbrocini G, Stingeni L, Napolitano M. The role of occupational dermatology in the COVID-19 outbreak. Contact Dermatitis. 2020;83(2):174-175. https://doi.org/10.1111/cod.13568
7. Han HS, Shin SH, Park JW, Li K, Kim BJ, Yoo KH. Changes in skin characteristics after using respiratory protective equipment (medical masks and respirators) in the COVID-19 pandemic among healthcare workers. Contact Dermatitis. 2021 Apr 4:10.1111/cod.13855. https://doi.org/10.1111/cod.13855
8. Sanghvi AR. COVID-19: An overview for dermatologists. Int J Dermatol. 2020;59(12):1437-1449. https://doi.org/10.1111/ijd.15257
9. MacGibeny MA, Wassef C. Preventing adverse cutaneous reactions from amplified hygiene practices during the COVID-19 pandemic: how dermatologists can help through anticipatory guidance. Arch Dermatol Res. 2021;313(6):501-503. https://doi.org/10.1007/s00403-020-02086-x
10. Lee EB, Lobl M, Ford A, DeLeo V, Adler BL, Wysong A. What Is New in Occupational Allergic Contact Dermatitis in the Year of the COVID Pandemic? Curr Allergy Asthma Rep. 2021;21(4):26. https://doi.org/10.1007/s11882-021-01000-3
11. Yu J, Chen JK, Mowad CM, Reeder M, Hylwa S, Chisolm S, Dunnick CA, Goldminz AM, Jacob SE, Wu PA, Zippin J, Atwater AR. Occupational dermatitis to facial personal protective equipment in health care workers: A systematic review. J Am Acad Dermatol. 2021;84(2):486-494. https://doi.org/10.1016/j.jaad.2020.09.074
12. Goh CF, Ming LC, Wong LC. Dermatologic reactions to disinfectant use during the COVID-19 pandemic. Clin Dermatol. 2021;39(2):314-322. https://doi.org/10.1016/j.clindermatol.2020.09.005
13. Battista RA, Ferraro M, Piccioni LO, Malzanni GE, Bussi M. Personal Protective Equipment (PPE) in COVID 19 Pandemic: Related Symptoms and Adverse Reactions in Healthcare Workers and General Population. J Occup Environ Med. 2021;63(2):e80-e85. https://doi.org/10.1097/JOM.0000000000002100
14. Sanghvi AR. COVID-19: An overview for dermatologists. Int J Dermatol. 2020;59(12):1437-1449. https://doi.org/10.1111/ijd.15257
15. Bambi S, Giusti GD, Galazzi A, Mattiussi E, Comisso I, Manici M, Rosati M, Lucchini A. Pressure Injuries Due to Personal Protective Equipment in COVID-19 Critical Care Units. Am J Crit Care. 2021;30(4):287-293. https://doi.org/10.4037/ajcc2021178
16. Chaiyabutr C, Sukakul T, Pruksaeakanan C, Thumrongtharadol J, Boonchai W. Adverse skin reactions following different types of mask usage during the COVID-19 pandemic. J Eur Acad Dermatol Venereol. 2021;35(3):e176-e178. https://doi.org/10.1111/jdv.17039
17. Techasatian L, Lebsing S, Uppala R, Thaowandee W, Chaiyarit J, Supakunpinyo C, Panombualert S, Mairiang D, Saengnipanthkul S, Wichajarn K, Kiatchoosakun P, Kosalaraksa P. The Effects of the Face Mask on the Skin Underneath: A Prospective Survey During the COVID-19 Pandemic. J Prim Care Community Health. 2020;11:2150132720966167. https://doi.org/10.1177/2150132720966167
18. Mekonnen TH, Yenealem DG, Tolosa BM. Self-report occupational-related contact dermatitis: prevalence and risk factors among healthcare workers in Gondar town, Northwest Ethiopia, 2018-a cross-sectional study. Environ Health Prev Med. 2019;24(1):11. https://doi.org/10.1186/s12199-019-0765-0
19. Quintana-Díaz MA, Aguilar-Salinas CA. Universal masking during COVID-19 pandemic - current evidence and controversies. Rev Invest Clin. 2020;72(3):144-150. https://doi.org/10.24875/RIC.20000196
20. Montero-Vilchez T, Martinez-Lopez A, Cuenca-Barrales C, Rodriguez-Tejero A, Molina-Leyva A, Arias-Santiago S. Impact of Gloves and Mask Use on Epidermal Barrier Function in Health Care Workers. Dermatitis. 2021;32(1):57-62. https://doi.org/10.1097/DER.0000000000000682
21. Damiani G, Gironi LC, Pacifico A, Cristaudo A, Malagoli P, Allocco F, Bragazzi NL, Linder DM, Santus P, Buja A, Savoia P, Pigatto PD; COVID-19 Dermatologic Italian Task Force, Young Dermatologists Italian Network. Masks use and facial dermatitis during COVID-19 outbreak: is there a difference between CE and non-CE approved masks? Multi-center, real-life data from a large Italian cohort. Ital J Dermatol Venerol. 2021;156(2):220-225. https://doi.org/10.23736/S2784-8671.21.06895-4
22. Lin P, Zhu S, Huang Y, Li L, Tao J, Lei T, Song J, Liu D, Chen L, Shi Y, Jiang S, Liu Q, Xie J, Chen H, Duan Y, Xia Y, Zhou Y, Mei Y, Zhou X, Wu J, Fang M, Meng Z, Li H. Adverse skin reactions among healthcare workers during the coronavirus disease 2019 outbreak: a survey in Wuhan and its surrounding regions. Br J Dermatol. 2020;183(1):190-192. https://doi.org/10.1111/bjd.19089
23. Montero-Vilchez T, Cuenca-Barrales C, Martinez-Lopez A, Molina-Leyva A, Arias-Santiago S. Skin adverse events related to personal protective equipment: a systematic review and meta-analysis. J Eur Acad Dermatol Venereol. 2021;35(10):1994-2006. https://doi.org/10.1111/jdv.17436
24. Marraha F, Al Faker I, Charif F, Chahoub H, Benyamna Y, Rahmani N, Kabbou S, Rkiek Y, Najdi A, Gallouj S. Skin Reactions to Personal Protective Equipment among First-Line COVID-19 Healthcare Workers: A Survey in Northern Morocco. Ann Work Expo Health. 2021;65(8):998-1003. https://doi.org/10.1097/JOM.0000000000002100
25. Metin N, Turan Ç, Utlu Z. Changes in dermatological complaints among healthcare professionals during the COVID-19 outbreak in Turkey. Acta Dermatovenerol Alp Pannonica Adriat. 2020;29(3):115-122. https://doi.org/10.15570/actaapa.2020.25
26. Elston DM. Occupational skin disease among health care workers during the coronavirus (COVID-19) epidemic. J Am Acad Dermatol. 2020;82(5):1085-1086. https://doi.org/10.1016/j.jaad.2020.03.012
27. Park SJ, Han HS, Shin SH, Yoo KH, Li K, Kim BJ, Seo SJ, Park KY. Adverse skin reactions due to use of face masks: a prospective survey during the COVID-19 pandemic in Korea. J Eur Acad Dermatol Venereol. 2021;35(10):e628-e630. https://doi.org/10.1111/jdv.17447
28. Kiely LF, Moloney E, O'Sullivan G, Eustace JA, Gallagher J, Bourke JF. Irritant contact dermatitis in healthcare workers as a result of the COVID-19 pandemic: a cross-sectional study. Clin Exp Dermatol. 2021;46(1):142-144. https://doi.org/10.1111/ced.14397
29. Damiani G, Gironi LC, Grada A, Kridin K, Finelli R, Buja A, Bragazzi NL, Pigatto PDM, Savoia P. COVID-19 related masks increase severity of both acne (maskne) and rosacea (mask rosacea): Multi-center, real-life, telemedical, and observational prospective study. Dermatol Ther. 2021;34(2):e14848. https://doi.org/10.1111/dth.14848
30. Damiani G, Gironi LC, Kridin K, Pacifico A, Buja A, Bragazzi NL, Spalkowska M, Pigatto PDM, Santus P; Young Dermatologists Italian Network, Savoia P. Mask-induced Koebner phenomenon and its clinical phenotypes: A multicenter, real-life study focusing on 873 dermatological consultations during COVID-19 pandemics. Dermatol Ther. 2021;34(2):e14823. https://doi.org/10.1111/dth.14823
31. Seirafianpour F, Sodagar S, Pour Mohammad A, Panahi P, Mozafarpoor S, Almasi S, Goodarzi A. Cutaneous manifestations and considerations in COVID-19 pandemic: A systematic review. Dermatol Ther. 2020;33(6):e13986. https://doi.org/10.1111/dth.13986
32. Barnawi GM, Barnawi AM, Samarkandy S. The Association of the Prolonged Use of Personal Protective Equipment and Face Mask During COVID-19 Pandemic With Various Dermatologic Disease Manifestations: A Systematic Review. Cureus. 2021;13(7):e16544. https://doi.org/10.7759/cureus.16544
33. Uthayakumar AK, Panagou E, Manam S, Schauer A, Veraitch O, Walker S, Edmonds E, Crawley J, Martyn-Simmons C. PPE-associated dermatoses: effect on work and wellbeing. Future Healthc J. 2021;8(1):e67-e69. https://doi.org/10.7861/fhj.2020-0210
34. Lee HC, Goh CL. 'Occupational dermatoses from Personal Protective Equipment during the COVID-19 pandemic in the tropics - A Review'. J Eur Acad Dermatol Venereol. 2021;35(3):589-596. https://doi.org/10.1111/jdv.16925
35. Gül Ü. COVID-19 and dermatology. Turk J Med Sci. 2020;50(8):1751-1759. https://doi.org/10.3906/sag-2005-182.10.3906/sag-2005-182
36. Galanis P, Vraka I, Fragkou D, Bilali A, Kaitelidou D. Impact of personal protective equipment use on health care workers' physical health during the COVID-19 pandemic: A systematic review and meta-analysis. Am J Infect Control. 2021;49(10):1305-1315. https://doi.org/10.1016/j.ajic.2021.04.084
37. Hu K, Fan J, Li X, Gou X, Li X, Zhou X. The adverse skin reactions of health care workers using personal protective equipment for COVID-19. Medicine (Baltimore). 2020;99(24):e20603. https://doi.org/10.1097/MD.0000000000020603
38. Daye M, Cihan FG, Durduran Y. Evaluation of skin problems and dermatology life quality index in health care workers who use personal protection measures during COVID-19 pandemic. Dermatol Ther. 2020;33(6):e14346. https://doi.org/10.1111/dth.14346
39. Techasatian L, Lebsing S, Uppala R, Thaowandee W, Chaiyarit J, Supakunpinyo C, Panombualert S, Mairiang D, Saengnipanthkul S, Wichajarn K, Kiatchoosakun P, Kosalaraksa P. The Effects of the Face Mask on the Skin Underneath: A Prospective Survey During the COVID-19 Pandemic. J Prim Care Community Health. 2020;11:2150132720966167. https://doi.org/10.1177/2150132720966167
40. Lan J, Song Z, Miao X, Li H, Li Y, Dong L, Yang J, An X, Zhang Y, Yang L, Zhou N, Yang L, Li J, Cao J, Wang J, Tao J. Skin damage among health care workers managing coronavirus disease-2019. J Am Acad Dermatol. 2020;82(5):1215-1216. https://doi.org/10.1016/j.jaad.2020.03.014
41. Hadjieconomou S, Hughes J, Kamath S. Occupational skin disease during the COVID-19 pandemic, as captured in a Dermatology staff clinic in the United Kingdom. J Eur Acad Dermatol Venereol. 2020;34(11):e670-e671. https://doi.org/10.1111/jdv.16754
42. ZahrAllayali A, Al-Doboke A, Alosaimy R, Alabbasi R, Alharbi S, Fageeh S, Altayyar S, Azher R. The Prevalence and Clinical Features of Skin Irritation Caused by Infection Prevention Measures During COVID-19 in the Mecca Region, Saudi Arabia. Clin Cosmet Investig Dermatol. 2021;14:889-899. https://doi.org/10.2147/CCID.S309681
43. Zhang M, Wang L, Yu S, Sun G, Lei H, Wu W. Status of occupational protection in the COVID-19 Fangcang Shelter Hospital in Wuhan, China. Emerg Microbes Infect. 2020;9(1):1835-1842. https://doi.org/10.1080/22221751.2020.1803145
44. Kantor J. Behavioral considerations and impact on personal protective equipment use: Early lessons from the coronavirus (COVID-19) pandemic. J Am Acad Dermatol. 2020;82(5):1087-1088. https://doi.org/10.1016/j.jaad.2020.03.013
45. Yan Y, Chen H, Chen L, Cheng B, Diao P, Dong L, Gao X, Gu H, He L, Ji C, Jin H, Lai W, Lei T, Li L, Li L, Li R, Liu D, Liu W, Lu Q, Shi Y, Song J, Tao J, Wang B, Wang G, Wu Y, Xiang L, Xie J, Xu J, Yao Z, Zhang F, Zhang J, Zhong S, Li H, Li H. Consensus of Chinese experts on protection of skin and mucous membrane barrier for healthcare workers fighting against coronavirus disease 2019. Dermatol Ther. 2020;33(4):e13310. https://doi.org/10.1111/dth.13310
46. Burns ES, Pathmarajah P, Muralidharan V. Physical and psychological impacts of handwashing and personal protective equipment usage in the COVID-19 pandemic: A UK based cross-sectional analysis of healthcare workers. Dermatol Ther. 2021;34(3):e14885. https://doi.org/10.1111/dth.14885
47. Oranges T, Janowska A, Dini V. Reply to: "Skin damage among health care workers managing coronavirus disease-2019". J Am Acad Dermatol. 2020;82(6):e233-e234.https://doi.org/10.1016/j.jaad.2020.04.003
48. Yap KK, Murali M, Tan Z, Zhou X, Li L, Masen MA. Wax-oil lubricants to reduce the shear between skin and PPE. Sci Rep. 2021;11(1):11537. https://doi.org/10.14469/hpc/8076
49. Zhou N, Yang L, Li Y, Yang J, Yang L, An X, Zhang Y, Suo H, Du H, Zhu J, Tao J, Dong L. Hydrogel patches alleviate skin injuries to the cheeks and nasal bridge caused by continuous N95 mask use. Dermatol Ther. 2020;33(6):e14177. https://doi.org/10.1111/dth.14177
50. Desai SR, Kovarik C, Brod B, James W, Fitzgerald ME, Preston A, Hruza GJ. COVID-19 and personal protective equipment: Treatment and prevention of skin conditions related to the occupational use of personal protective equipment. J Am Acad Dermatol. 2020;83(2):675-677. https://doi.org/10.1016/j.jaad.2020.05.032
51. Abtahi-Naeini B. Frequent handwashing amidst the COVID-19 outbreak: prevention of hand irritant contact dermatitis and other considerations. Health Sci Rep. 2020;3(2):e163.https://doi.org/10.1002/hsr2.163
52. Sharma P, Goel N, Dogar K, Bhalla M, Thami GP, Punia K. Adverse skin reactions related to PPE among healthcare workers managing COVID-19. J Eur Acad Dermatol Venereol. 2021;35(8):e481-e483. https://doi.org/10.1111/jdv.17290
53. Sud SR. COVID-19 and Keeping Clean: A Narrative Review To Ascertain the Efficacy of Personal Protective Equipment To Safeguard Health Care Workers Against SARS-CoV-2. Hosp Pediatr.;10(7):570-576. https://doi.org/10.1542/hpeds.2020-0135
Рецензия
Для цитирования:
Галимова Н.И. Поражения кожи у медицинских работников в период пандемии СOVID-19, ассоциированные со средствами индивидуальной защиты. Фундаментальная и клиническая медицина. 2021;6(4):122-131. https://doi.org/10.23946/2500-0764-2020-6-4-122-131
For citation:
Galimova N.I. Skin lesions associated with personal protective equipment in medical workers during the COVID-19 pandemic. Fundamental and Clinical Medicine. 2021;6(4):122-131. (In Russ.) https://doi.org/10.23946/2500-0764-2020-6-4-122-131