Extracerebral manifestations of acute cerebral insufficiency in patients in critical condition
https://doi.org/10.23946/2500-0764-2022-7-3-64-73
Abstract
Acute cerebral insufficiency is a life-threatening condition defined by a loss of basic and higher nervous activity, as well as neuronal regulation of vital organs. Along with the signs and symptoms of brain damage, acute cerebral insufficiency is often accompanied by manifestations from other vital organs (i.e., respiratory, cardiovascular, gastrointestinal, urinary and immune systems as well as haemostasis), significantly complicating the disease course. Among the critical consequences following acute cerebral insufficiency are: 1) neurogenic endocrine disorders including hypopituitarism and impaired secretion of antidiuretic hormone which are notable for electrolyte imbalance; 2) healthcare-associated infections such as congestive pneumonia, ventriculitis, and pressure ulcers. In the worst-case scenario, acute cerebral insufficiency results in a multiple organ dysfunction syndrome. Here we describe epidemiology, pathophysiology, signs, symptoms, prevention, and treatment of vital organs in patients with acute cerebral insufficiency.
About the Authors
A. A. Zadvornov
Kuzbass Regional Children' Clinical Hospital
Russian Federation
Russian Federation
Dr. Alexey A. Zadvornov, MD, PhD, anaesthesiologist and critical care physician, Neonatal Intensive Care Unit
21, Voroshilova Street, Kemerovo, 650056, Russian Federation
E. V. Grigoriev
Kemerovo State Medical University
Russian Federation
Russian Federation
Prof. Evgeny V. Grigoriev, MD, DSc, Professor, Head of the Department of Anesthesiology, Critical Care Medicine, Traumatology and Orthopaedics
22а, Voroshilova Street, Kemerovo, 650056, Russian Federation
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For citations:
Zadvornov A.A., Grigoriev E.V. Extracerebral manifestations of acute cerebral insufficiency in patients in critical condition. Fundamental and Clinical Medicine. 2022;7(3):64-73. (In Russ.) https://doi.org/10.23946/2500-0764-2022-7-3-64-73
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