Prevalence and associated facors of metabolic syndrome in hospitilized patients: a cross-sectional study
https://doi.org/10.23946/2500-0764-2026-11-2-125-135
Abstract
Aim. To assess the prevalence of MetS and identify factors associated with its presence among hospitalized patients.
Materials and methods. We conducted an observational analytical cross-sectional study on a sample of 187 patients from the therapeutic department of Sechenov University Clinical Hospital № 4 (study period: April 2024 – January 2025). Data included medical records and face-to-face interviewing. Participants were divided into two groups: 84 with MetS and 103 without. Categorical variables were compared using Pearson's chi-square and Fisher's exact tests. Logistic regression adjusted for sex and age was performed, followed by multivariate analysis.
Results. The prevalence of MetS among hospitalized patients was 44.92 %. MetS was significantly less common in individuals aged 18–44 years and more prevalent among women. In the MetS group, the most common combination (44.85 % of patients) was abdominal obesity combined with two additional criteria. According to logistic regression and multivariate analysis, the factors most strongly associated with MetS were: presence of hormonal disorders in first-degree relatives (OR = 2,92; 95 % CI: 1,07–8,29; p = 0,04), consumption of animal fats and foods containing hidden fats 4–5 times per week (OR = 8,73; 95 % CI: 2,65–33,29; p = 0,001), and salt intake 5 and more g/day (OR = 3,77; 95 % CI: 1,24–12,31; p = 0,02).
Conclusion. The identified association between MetS and hereditary predisposition, as well as excessive intake of fats and salt, underscores the necessity of thorough family history collection and its assessment at the patient's first visit to identify risk groups and enhance motivation for dietary correction. Further prospective studies are required to confirm causal relationships.
About the Authors
A. G. Chigir
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Dr. Alexandra G. Chigir, MD, Postgraduate Student, Department of Epidemiology and Evidence-Based Medicine, F.F. Erismann Institute of Public Health
Trubetskaya Street, 8, Building 2, Moscow, 119048
R. V. Polibin
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Dr. Roman V. Polibin, MD, Cand. Sci. (Medicine), Associate Professor, Department of Epidemiology and Evidence-based Medicine, F.F. Erismann Institute of Public Health
Trubetskaya Street, 8, Building 2, Moscow, 119048
N. A. Dragomiretskaya
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Prof. Natalia A. Dragomiretskaya, MD, Dr. Sci (Medicine), Professor, Department of Faculty Therapy № 2, N.V. Sklifosovsky Institute of Clinical Medicine
Trubetskaya Street, 8, Building 2, Moscow, 119048
References
1. Shlyakhto EV, Nedogoda SV, Babenko AYu, Arutyunov GP, Drapkina OM, Kobalava ZhD, et al. Concept of an interdisciplinary consensus document on cardiovascular-renal-hepatic-metabolic syndrome. Russian Journal of Cardiology. 2025;30(1S):6533. (In Russ.). https:// doi.org/10.15829/1560-4071-2025-6533
2. Islam MS, Wei P, Suzauddula M, Nime I, Feroz F, Acharjee M, et al. The interplay of factors in metabolic syndrome: understanding its roots and complexity. Mol Med. 2024;30(1):279. https://doi.org/10.1186/s10020-024-01019-y
3. Chew NWS, Mehta A, Goh R, Koh J, Chen Y, Chong B, et al. The global cardiovascular-liver-metabolic syndemic: epidemiology, trends and challenges. Nat Rev Cardiol. 2026;23(4):219–238. https://doi.org/10.1038/s41569-025-01220-4
4. Balanova YuA, Imaeva AE, Kutsenko VA, Kapustina AV, Muromtseva GA, Evstifeeva SE, et al. Metabolic syndrome and its associations with socio-demographic and behavioral risk factors in the Russian population aged 25-64 years. Cardiovascular Therapy and Prevention. 2020;19(4):2600. (In Russ.). https://doi.org/10.15829/1728-8800-2020-2600
5. Grinshtein YuI, Shabalin VV, Ruf RR, Shalnova SA. The prevalence of metabolic syndrome in the Krasnoyarsk Krai population and the features of its association with hyperuricemia. Russian Journal of Cardiology. 2020;25(6):3852. (In Russ.). https://doi.org/10.15829/1560-4071-2020-3852
6. Mendoza-Caamal EC, Barajas-Olmos F, García-Ortiz H, Cicerón-Arellano I, Martínez-Hernández A, Córdova EJ, et al. Metabolic syndrome in indigenous communities in Mexico: a descriptive and cross-sectional study. BMC Public Health. 2020;20(1):339. https://doi.org/10.1186/s12889-020-8378-5
7. Dolich VN, Komleva NE, Mazilov SI, Zaikina IV. Prevalence of metabolic syndrome among the working population of the Saratov region and its relationship with medical and social factors. Sibirskij nauchnyj medicinskij zhurnal = Siberian Scientific Medical Journal. 2024;44(4):214–222. (In Russ.). https://doi.org/10.18699/SSMJ2024042
8. León-Samaniego GF, Romero Urréa HE, Espinoza-Carrasco F, Llimaico Noriega MJ, Encalada Campos GE, Herrera P, et al. Metabolic Syndrome Indicators and Cardiovascular/Endocrine Risks in Rural Ecuador: A Cross-Sectional Study. J Pers Med. 2025;15(3):78. https://doi.org/10.3390/jpm15030078
9. Bestavashvili A, Glazachev O, Bestavashvili A, Suvorov A, Zhang Y, Zhang X, et al. Intermittent Hypoxic-Hyperoxic Exposures Effects in Patients with Metabolic Syndrome: Correction of Cardiovascular and Metabolic Profile. Biomedicines. 2022;10(3):566. https://doi.org/10.3390/biomedicines10030566
10. Li Y, Sun Y, Wu H, Yang P, Huang X, Zhang L, et al. Metabolic syndromes increase significantly with the accumulation of bad dietary habits. J Nutr Health Aging. 2024;28(2):100017. https://doi.org/10.1016/j.jnha.2023.100017
11. Korolev AA, Lopukhova IV, Nikitenko EI, Denisova EL, Kirpichenkova EV, Onishchenko GG. Hygienic assessment of dietary intake of saturated fatty acids and trans isomers of fatty acids. Hygiene and Sanitation. 2024;103(6):571–576. (In Russ.). https://doi.org/10.47470/0016-9900-2024-103-6-571-576
12. Ribeiro NG, Lelis DF, Molina MDCB, Schmidt MI, Duncan BB, Griep RH, et al. The high salt intake in adults with metabolic syndrome is related to increased waist circumference and blood pressure: the Brazilian Longitudinal Study of Adult Health study (ELSA-Brasil). Nutrition. 2023;114:112108. https://doi.org/10.1016/j.nut.2023.112108
13. Alowfi A, Binladen S, Irqsous S, Khashoggi A, Khan MA, Calacattawi R. Metabolic Syndrome: Prevalence and Risk Factors among Adolescent Female Intermediate and Secondary Students in Saudi Arabia. Int J Environ Res Public Health. 2021;18(4):2142. https://doi.org/10.3390/ijerph18042142
14. Ling S, Huang L, Lia T, Xie D, Qin X, Tian C, et al. Identification and validation of core genes associated with polycystic ovary syndrome and metabolic syndrome. Medicine (Baltimore). 2024;103(42):e40162. https://doi.org/10.1097/MD.0000000000040162
15. Kiseleva EV, Pigarova EA, Mokrysheva NG. The evolution of body composition assessment: from body mass index to body composition profiling. FOCUS. Endocrinology. 2023;4(2):12–18. (In Russ.). https://doi.org/10.15829/1560-4071-2023-13 EDN: NHKQST.
16. Sheng L, Yang G, Chai X, Zhou Y, Sun X, Xing Z. Glycemic variability evaluated by HbA1c rather than fasting plasma glucose is associated with adverse cardiovascular events. Front Endocrinol (Lausanne). 2024;15:1323571. https://doi.org/10.3389/fendo.2024.1323571
Review
For citations:
Chigir A.G., Polibin R.V., Dragomiretskaya N.A. Prevalence and associated facors of metabolic syndrome in hospitilized patients: a cross-sectional study. Fundamental and Clinical Medicine. 2026;11(2):125-135. (In Russ.) https://doi.org/10.23946/2500-0764-2026-11-2-125-135
Views:
38
JATS XML
Email this article 