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Risk factors of hepatitis B in patients on hemodialysis: a systematic review

https://doi.org/10.23946/2500-0764-2019-4-2-107-119

Abstract

Aim. To perform a systematic review of hepatitis В risk factors in patients receiving hemodialysis.

Materials and Methods. We screened English-and Russian-language databases for relevant obser- vational cohort studies. Screening of publications and extraction of primary data were carried out in accordance with the Cochrane recommendations. The significance of hepatitis В risk factors was given in odds ratios with 95% confidence intervals.

Results. All included primary studies demonstrated that patients on hemodialysis are at high risk of acquiring blood-borne diseases due to the combination of various risk factors. For example, duration of hemodialysis > 2 years significantly increased hepatitis В risk (OR = 2.24, 1QR 1.052.08).

Conclusion. A critical attitude to modifiable and non-modifiable risk factors increases the effectiveness of epidemiological surveillance and infection control and ensures quality and safety of medical care for the patients receiving hemodialysis.

About the Authors

D. V. Kvashnina
PrivoIzhskiy Research Medical University
Russian Federation

Dr. Daria V. Kvashnina - MD, PhD, Senior Lecturer, Department ofEpidemiology, Microbiology and Evidence-Based medicine.

70, Gagarina Prospekt, N. Novgorod, 603081



O. V. Kovalishena
PrivoIzhskiy Research Medical University
Russian Federation

Prof. Olga V. Kovalishena - MD, DSc, Head ofthe Department ofEpidemiology, Microbiology and Evidence-Based medicine.

10/1, Minin and Pozharsky Square, Nizhniy Novgorod, 603005



N. V. Saperkin
Utrecht University
Netherlands

Dr. Nikolay V. Saperkin - MD, PhD, Researcher.

Domplein 29, 3512 JE, Utrecht



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Kvashnina D.V., Kovalishena O.V., Saperkin N.V. Risk factors of hepatitis B in patients on hemodialysis: a systematic review. Fundamental and Clinical Medicine. 2019;4(2):107-119. (In Russ.) https://doi.org/10.23946/2500-0764-2019-4-2-107-119

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