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Prediction of perinatal complications of gestational diabetes

https://doi.org/10.23946/2500-0764-2019-4-4-19-25

Abstract

Aim. To develop a tool for the prediction of perinatal complications in pregnant women with gestational diabetes utilizing conventional and ultrasound markers of diabetic fetopathy.

Materials and Methods. We analyzed 128 case histories of women who suffered from gestational diabetes. Among their newborns, 35 had clinical manifestations of maternal hyperglycemia (birth weight > 90th percentile, neonatal hyperglycemia, respiratory distress syndrome, and neonatal jaundice) while 74 were free of the indicated signs and symptoms.

Results. Risk factors of maternal hyperglycemia manifestations in neonates included family history of diabetes mellitus type 2, obesity, and pre-eclampsia. Maternal hyperglycemia was significantly associated with the higher risk of adverse perinatal outcomes. A combination of ≥ 4 ultrasound оценке markers of a diabetic fetopathy permitted the diagnosis of the fetal macrosomia. Conclusion. Ultrasound markers of diabetic fetopathy have limited sensitivity in the prediction of perinatal complications after gestational diabetes.

About the Authors

O. V. Rozhkova
Altai State Medical University, Barnaul, Russian Federation; Altai Regional Clinical Perinatal Centre
Russian Federation

Dr. Olga V. Rozhkova, Dr., PhD Student, Department of Obstetrics and Gynecology, Altai State Medical University(40, Lenina Prospekt, Barnaul,656038, Russian Federation); Ultrasound Specialist, Altai Regional Clinical Perinatal Center

40, Lenina Prospekt, Barnaul, 656038



O. V. Remneva
Altai State Medical University, Barnaul, Russian Federation; Altai Regional Clinical Perinatal Centre
Russian Federation

Olga V. Remneva, Prof., MD, DSc, Professor, Head of the Department of Obstetrics and Gynecology, Altai State Medical University

40, Lenina Prospekt, Barnaul, 656038



N. V. Trukhacheva
Altai State Medical University, Barnaul, Russian Federation
Russian Federation

Nina V. Trukhacheva, Dr.,  PhD, Associate Professor, Department of Physics and Informatics

40, Lenina Prospekt, Barnaul, 656038



References

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Review

For citations:


Rozhkova O.V., Remneva O.V., Trukhacheva N.V. Prediction of perinatal complications of gestational diabetes. Fundamental and Clinical Medicine. 2019;4(4):19-25. (In Russ.) https://doi.org/10.23946/2500-0764-2019-4-4-19-25

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ISSN 2500-0764 (Print)
ISSN 2542-0941 (Online)