Factors affecting the effectiveness of assisted reproductive technologies in St. Petersburg’s medical organizations

Aim. Comprehensive epidemiological assessment of factors affecting the effectiveness of the infertility treatment in medical organizations of St. Petersburg.

Materials and Methods. The effectiveness of assisted reproductive technology programs in St. Petersburg reproductive centers was evaluated by analyzing the respective database for infertility treatment in 2013-2017. We retrospectively examined 843 patient records that were submitted to one of the St. Petersburg reproductive centers in 2014-2017 with the following survey and in-depth clinical examination of 129 couples before in vitro fertilisation.

Results. Risk factors of infertility included vaginal dysbiosis (OR = 7.5 (95% CI 1.04-54.1)), Trichomonas vaginalis infection (OR= 2.6 (95% CI 1.12 - 6.4)), and smoking (OR = 2.6 (95% CI 1.0 - 6.5)).

Conclusion. Optimised screening of couples before in vitro fertilisation may increase the effectiveness of assisted reproductive technology programs. Stimulation of the population's commitment to a healthy lifestyle including non-smoking policy should be one of the main directions to prevent infertility.

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