Нypeгtriploidy as a cause of early embryonic arrest
https://doi.org/10.23946/2500-0764-2020-5-1-99-102
Abstract
Chromosomal abnormalities are a leading cause of early embryonic arrest Identification of genetic abnormalities incompatible with embryonic development significantly contributes to the understanding of early embryonic arrest causes and to the development of prevention strategies. Here we describe a case of hypertriploid abortus with 70, XXY,+16 karyotype. This chromosomal abnormality led to the early embryonic arrest at 4 weeks and 5 days of pregnancy.
The clinical report emphasizes the necessity for the cytogenetic analysis of abortion material in the patients who underwent a reproductive failure.
About the Authors
A. N. Volkov
Kemerovo State Medical University; Belyaev Kemerovo Regional Clinical Hospital
Russian Federation
Russian Federation
Dr. Alexey N. Volkov - PhD, Associate Professor, Department of Biology, Genetics and Parasitology; Senior Researcher, Central Research Laboratory, KSMU; Biologist, Department of Genetic Counseling Unit, Belyaev KRCH.
22a, Voroshilova Street, Kemerovo, 650056; 22, Oktyabr'skiy Avenue, Kemerovo, 650056
L. V. Nacheva
Kemerovo State Medical University
Russian Federation
Russian Federation
Prof. Lyubov V Nacheva - MD, PhD, Professor, Head of the Department of Biology, Genetics, and Parasitology.
22a, Voroshilova Street, Kemerovo, 650056
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Review
For citations:
Volkov A.N., Nacheva L.V. Нypeгtriploidy as a cause of early embryonic arrest. Fundamental and Clinical Medicine. 2020;5(1):99-102. (In Russ.) https://doi.org/10.23946/2500-0764-2020-5-1-99-102
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