Use of internal thoracic artery as a conduit protects coronary artery in the long-term period after coronary artery bypass graft surgery
https://doi.org/10.23946/2500-0764-2023-8-1-80-92
Abstract
Aim. To assess whether the internal thoracic artery (ITA) is able to protect coronary artery (CA) after coronary artery bypass graft (CABG) surgery.
Material and Methods. Having performed coronary angiography in the long term after CABG surgery, we evaluated 102 angiograms by visual analysis and using Gensini score and SYNTAX score. Using these parameters, we investigated the association of internal thoracic artery and saphenous vein grafts with anatomy and pathology of the coronary artery.
Results. Calculation of Gensini score revealed that use of ITA grafts was associated with mild coronary atherosclerosis [4 (0; 17)] as compared with SV grafts [32 (2 ; 32)]. Relative increase of atherosclerotic burden in the coronary artery was 21.05% for the ITA grafts and 102.87% for the SV grafts. Lesion growth rate was significantly higher after using SV grafts than in case with ITA grafts (p = 0.0002)
Conclusion. ITA grafts reduce progression of atherosclerosis in bypassed coronary arteries in comparison with SV grafts.
About the Authors
A. V. Frolov
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation
Russian Federation
Dr. Alexey V. Frolov, MD, PhD, Senior Research Fellow, Laboratory of Endovascular and Reconstructive Surgery, Department of Cardiovascular Surgery
6, Sosnovy Boulevard, Kemerovo, 650002
N. I. Zagorodnikov
Kuzbass Clinical Cardiological Dispensary
Russian Federation
Russian Federation
Dr. Nikita I. Zagorodnikov, MD, Cardiovascular Surgeon, Neurosurgery Unit
6, Sosnovy Boulevard, Kemerovo, 650002
R. S. Tarasov
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation
Russian Federation
Dr. Roman S. Tarasov, MD, DSc, Head of the Laboratory of Endovascular and Reconstructive Surgery, Department of Cardiovascular Surgery
6, Sosnovy Boulevard, Kemerovo, 650002
E. V. Grigoriev
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation
Russian Federation
Prof. Evgeny V. Grigoriev, MD, DSc, Professor, Chief Scientific Officer
6, Sosnovy Boulevard, Kemerovo, 650002
S. V. Ivanov
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation
Russian Federation
Dr. Sergey V. Ivanov, MD, DSc, Leading Research Fellow, Laboratory of Endovascular and Reconstructive Surgery, Department of Cardiovascular Surgery
6, Sosnovy Boulevard, Kemerovo, 650002
L. S. Barbarash
Research Institute for Complex Issues of Cardiovascular Diseases
Russian Federation
Russian Federation
Prof. Leonid S. Barbarash, MD, DSc, Professor, Academician of the Russian Academy of Sciences, Chief Researcher
6, Sosnovy Boulevard, Kemerovo, 650002
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Review
For citations:
Frolov A.V., Zagorodnikov N.I., Tarasov R.S., Grigoriev E.V., Ivanov S.V., Barbarash L.S. Use of internal thoracic artery as a conduit protects coronary artery in the long-term period after coronary artery bypass graft surgery. Fundamental and Clinical Medicine. 2023;8(1):80-92. (In Russ.) https://doi.org/10.23946/2500-0764-2023-8-1-80-92
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