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Clinical case of congenital quartana malaria

https://doi.org/10.23946/2500-0764-2025-10-4-128-134

Abstract

Aim. Description of a clinical case of congenital fourday malaria. Case study. Patient: Female, 56 days old, with thrombocytopenia and anaemia. Due to abnormal changes in the blood tests, a blood smear was prepared for microscopic examination. The digital CellaVision system detected giant platelets. Imaging revealed malaria Quartana: Plasmodium malariae. The CellaVision system did not detect gametocytes and schizonts and mistakenly classified them as platelets. of African descent and previously ill with unknown malaria, underwent treatment, showed no clinical symptoms. During pregnancy, there were no typical symptoms of malaria. After the birth of the child, jaundice was detected and a complete blood test was performed. Results were normal, but jaundice persisted and fever subsequently developed. A second blood test was carried out. After microscopic examination, the causative agent of Quartana malaria, Plasmodium malariae, was found. The diagnosis was confirmed by a positive PCR test. Conclusion. In epidemiologically malaria-friendly regions, caution should be exercised about the possibility of the disease and testing of pregnant women arriving from an area with a high risk of malaria transmission should be mandatory.

About the Authors

A. Yu. Vorozhishcheva
Novokuznetsk State Institute for Postgraduate Medical Education, Branch of the Russian Medical Academy of Continuous Professional Education
Russian Federation

Anna Yu. Vorozhishcheva, Сand. Sci. (Medicine), Associate Professor of the department of Microbiology

Stroiteley Avenue, 5, Novokuznetsk, Kemerovo region, 654005, Russia



N. S. Savinkina
Novokuznetsk City Clinical Hospital N 1 named after G.P. Kurbatov
Russian Federation

Natalia S. Savinkina, MD, doctor of clinical diagnostic laboratory, clinical department N 1

Bardina Avenue, 28, Novokuznetsk, 654057, Russia



T. V. Appelgans
Medical center SYNLAB GmbH
Germany

Tatyana V. Appelgans, MD, Dr Sci. (Medicine), expert in virtual microscopy and clinical chemistry

Gubener Strasse, 39, Augsburg,3986156, Germany



O. N. Vorobyeva
Novokuznetsk State Institute for Postgraduate Medical Education, Branch of the Russian Medical Academy of Continuous Professional Education
Russian Federation

Olga N. Vorobyeva, MD, Сand. Sci. (Medicine), Associate Professor of the department of Microbiology

Stroiteley Avenue, 5, Novokuznetsk, Kemerovo region, 654005, Russia



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Review

For citations:


Vorozhishcheva A.Yu., Savinkina N.S., Appelgans T.V., Vorobyeva O.N. Clinical case of congenital quartana malaria. Fundamental and Clinical Medicine. 2025;10(4):128-134. (In Russ.) https://doi.org/10.23946/2500-0764-2025-10-4-128-134

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ISSN 2500-0764 (Print)
ISSN 2542-0941 (Online)