Results of a Microbiological Study of Serogroup b Streptococcus in Patients of the Perinatal Center
https://doi.org/10.23946/2500-0764-2026-11-1-92-100
Abstract
Group B Streptococcus as a commensal can cause severe infectious diseases in newborns, posing a serious danger to their lives.
The aim of the study was to evaluate the frequency of registration of group B streptococcus in pregnant women, mothers and newborns Using a mini-laboratory – the analytical system «LifePad» Analyzer.
Materials and methods. The study was conducted in a group of pregnant women examined at 35−37 weeks of pregnancy, intranatally in the delivery room, as well as in newborns. Microbiological data were compared with clinical manifestations of newborns.
Results. Among pregnant women, S. agalactiae carriage was 4.4 %. In women examined in the delivery room, S. agalactiae was detected in 7.8 % of cases with a predominance of colonies in the vaginal contents and from the cervix. Every second pregnant woman had registration of polymicrobial associations. The use of the analytical system of the LIFEPAD analyzer in combination with reagents reduced the time for obtaining results on the presence of S. agalactiae to 60 minutes. When examining newborns, in 75.0 % of cases, streptococcus was seeded from the skin of the axilla. Generalized streptococcal infection was reported in 8.3 % of cases, localized in 16.7 % of newborns. Among the newborns of the second stage of nursing, generalized bacterial infection caused by S. agalactiae was reported in 8.0 % of cases, and localized in 40.0 %. The results of determining the sensitivity of S. agalactiae to antibacterial drugs revealed high resistance to tetracycline drugs, moderate to fluoroquinolones, macrolides and lincosamides. Some strains had a constitutive and inducible MLSb phenotype of antibiotic group resistance.
Conclusion. The relatively high incidence of infectious disease manifestation in newborns at risk requires attention to the diagnosis of Group B Streptococcus carriage in pregnant women.
Keywords
Supporting agencies: Part of the study was sponsored. Evotek-Mirai Genomix LLC provided the LifePad Analyzer and a kit for detecting group B Streptococcus (Streptococcus agalactiae) NK.
About the Authors
E. V. Naumkina
Omsk State Medical University of the Ministry of Health of the Russian Federation ; Urban Clinical Perinatal Center
Russian Federation
Russian Federation
Prof. Elena V. Naumkina, MD, Dr. Sci. (Medicine), Professor, Department of Microbiology, Virology and Immunology; Head of the Bacteriological Laboratory
Lenin Street, 12, Omsk, 644099
Herzen Street, 69, Omsk, 644007
L. V. Puzyreva
Omsk State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Dr. Larisa V. Puzyreva, MD, Dr. Sci. (Medicine), Head of the Department of Pediatric Infectious Diseases
Lenin Street, 12, Omsk, 644099
A. V. Dubrovskaya
Omsk State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Dr. Alena V. Dubrovskaya, MD, bacteriologist at the bacteriological laboratory
Lenin Street, 12, Omsk, 644099
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For citations:
Naumkina E.V., Puzyreva L.V., Dubrovskaya A.V. Results of a Microbiological Study of Serogroup b Streptococcus in Patients of the Perinatal Center. Fundamental and Clinical Medicine. 2026;11(1):92-99. (In Russ.) https://doi.org/10.23946/2500-0764-2026-11-1-92-100
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