Comparison of pregnancy course and outcomes in patients with uterine fibroids following uterine artery embolisation or myomectomy
https://doi.org/10.23946/2500-0764-2025-10-1-47-55
Abstract
Aim. To determine the optimal surgical treatment for uterine fibroids in patients with unfulfilled reproductive through the analysis of pregnancy course and outcomes following uterine artery embolization (UAE) and myomectomy.
Materials and Methods. The study assessed pregnancy course and outcomes, as well as neonatal conditions, in 147 patients including those who: 1) underwent UAE; 2) underwent myomectomy; 3) had untreated uterine fibroids; 4) did not have uterine fibroids. Data collection was conducted retrospectively by reviewing medical records, including case histories, pregnancy and delivery records, and newborn histories.
Results. There have been significant differences in pregnancy complications and delivery methods among the women who received distinct surgical treatments for uterine fibroids (myomectomy vs. UAE). In the third trimester, placental abnormalities were more frequent after UAE (12.5%) that after myomectomy (2.9%) but cesarian delivery was performed twice as low (47.0% vs. 94.3, respectively). Subsequent pregnancy risks were higher among the patients who had undergone myomectomy, as 50% of them experienced fibroid recurrence during the pregnancy and there were scars on the uterus as a result of myomectomy and cesarean section.
Conclusion. No new fibroid nodules as well as growth or vascularization of existing fibroids were observed after UAE, suggesting that it can be considered as a preferred treatment option, particularly for women who have not yet completed their reproductive plans.
About the Authors
V. A. Gurjeva
Altai State Medical University
Russian Federation
Russian Federation
Prof. Valentina A. Gurjeva, MD, Dr. Sci. (Medicine), Professor, Professor of the Department of Obstetrics and Gynecology
Lenina Prospekt 40, Barnaul, 656038
O. V. Kolyado
Altai State Medical University
Russian Federation
Russian Federation
Dr. Olga V. Kolyado, MD, Cand. Sci. (Medicine), Assistant Professor, Department of Obstetrics and Gynecology
Lenina Prospekt 40, Barnaul, 656038
O. V. Remneva
Altai State Medical University
Russian Federation
Russian Federation
Prof. Olga V. Remneva, MD, Dr. Sci. (Medicine), Professor, Head of the Department of Obstetrics and Gynecology
Lenina Prospekt 40, Barnaul, 656038
Yu. A. Shadeeva
Altai State Medical University
Russian Federation
Russian Federation
Dr. Yulia A. Shadeeva, MD, Cand. Sci. (Medicine), Associate Professor, Department of Obstetrics and Gynecology
Lenina Prospekt 40, Barnaul, 656038
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Review
For citations:
Gurjeva V.A., Kolyado O.V., Remneva O.V., Shadeeva Yu.A. Comparison of pregnancy course and outcomes in patients with uterine fibroids following uterine artery embolisation or myomectomy. Fundamental and Clinical Medicine. 2025;10(1):47-55. (In Russ.) https://doi.org/10.23946/2500-0764-2025-10-1-47-55
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