Preview

Fundamental and Clinical Medicine

Advanced search

Audit of maternal mortality in a large agricultural region of south Siberia

https://doi.org/10.23946/2500-0764-2026-11-1-82-91

Abstract

Aim. To audit the maternal mortality rate in the Altai Region, an agrarian region of southern Siberia, for the period 2015−2024 and assess the contribution of extragenital pathology and direct obstetric causes to its structure.

Materials and methods. A retrospective comparative analysis of the dynamics and structure of causes of maternal mortality for the period 2015−2024 was carried out in the number of 58 sectional observations in the Altai Region, characterized by a large territory, a population density below average and a predominance of women of fertile age living in rural areas (40.2 %).

Results. The maternal mortality rate in the large agricultural region of southern Siberia over the 10-year period under study was unstable. The sharp increase in its level in 2021 (73.7 per 100,000 live births) was due to COVID-19 and its consequences in the form of thromboembolic complications. The leading causes of maternal mortality in the post-pregnancy period are complications of cardiovascular diseases, HIV- infection, and cases of direct obstetric causes are determined by the social factor.

Conclusion. To achieve the goals of sustainable development at the regional level, interdisciplinary interaction and coordination of the efforts of specialized specialists for the correction of cardiovascular pathology, HIV-infection, effective social and psychological work with patients at high social risk is necessary.

About the Authors

I. V. Molchanova
Altai State Medical University ; Altai Regional Clinical Perinatal Center
Russian Federation

Dr. Irina V. Molchanova, MD, Cand. Sci. (Medicine), Chief; Assistant Professor, Department of the Obstetrics, Gynecology and postgraduate education

Lenina Street, 40, Barnaul, 656038 

Fomina Street, 154, Barnaul, 656045 



O. V. Koliado
Altai State Medical University ; Altai Regional Clinical Perinatal Center
Russian Federation

Dr. Olga V. Koliado, MD, Cand. Sci. (Medicine), Deputy Chief Physician for Clinical and Expert Work ; Assistant Professor, Department of the Obstetrics, Gynecology and postgraduate education #1

Lenina Street, 40, Barnaul, 656038 

Fomina Street, 154, Barnaul, 656045 



O. V. Remneva
Altai State Medical University
Russian Federation

Prof. Olga V. Remneva, MD, Dr. Sci. (Medicine), Professor, Head of the Department of the Obstetrics, Gynecology and Postgraduate Education #1

Lenina Street, 40, Barnaul, 656038 



I. D. Yaroshenko
Altai Regional Clinical Perinatal Center
Russian Federation

Dr. Irina D. Yaroshenko, MD, Medical Specialist of the Organizational and Methodological Department

Fomina Street, 154, Barnaul, 656045 



A. A. Volodina
Altai Regional Clinical Perinatal Center
Russian Federation

Dr. Alexandra A. Volodina, MD, Head of the Consulting and Diagnostic Department

Fomina Street, 154, Barnaul, 656045 



References

1. Filippov OS, Guseva EV, Pavlov KD. Global and Russian trends in Maternal mortality. Рroblemy reprodukcii. 2024;30(1):100–108. (in Russ.). https://doi.org/10.17116/repro202430011100

2. WHO. Fact sheets. Maternal mortality. 2023. Available at: https://www.who.int/ru/news-room/fact-sheets/detail/maternal-mortality. Accessed: February 02, 2025.

3. Filippov OS, Guseva EV. Maternal mortality in the Russian Federation in 2020: the first year of the pandemic. Рroblemy reprodukcii. 2022;28(1):8‑28. (in Russ.). https://doi.org/10.17116/repro2022280118

4. Samuel O, Zewotir T, North D. Decomposing the urban-rural inequalities in the utilisation of maternal health care services: evidence from 27 selected countries in sub-Saharan Africa. Reprod Health. 2021;18(1):216. https://doi.org/10.1186/s12978-021-01268-8

5. Cresswell JA, Alexander M, Chong MYC, Link HM, Pejchinovska M, Gazeley U, et al. Global and regional causes of maternal deaths 2009-20: a WHO systematic analysis. Lancet Global Health. 2025;13(4):e626–e634. https://doi.org/10.1016/S2214-109X(24)00560-6

6. WHO. Trends in maternal mortality 2000 to 2020: estimates by WHO, UNICEF, UNFPA, World Bank Group and UNDESA/Population Division. Executive summary. World Health Organization, 2023. Available at: https://www.who.int/publications/i/item/9789240068759 Accessed: Dezember 12, 2025.

7. Calvert C, John J, Nzvere FP, Cresswell JA, Fawcus S, Fottrell E, et al. Maternal mortality in the covid-19 pandemic: findings from a rapid systematic review. Glob Health Action. 2021;14(Suppl 1):1974677. https://doi.org/10.1080/16549716.2021.1974677

8. Belokrinitskaya TE, Shmakov RG, Frolova NI, Brum OYu, Krivoshchekova NA, Pavlova TYu, et al. Maternal mortality in the Far Eastern Federal District during the pre-epidemic period and three years of the COVID-19 pandemic. Akusherstvo i Ginekologiya. 2023;11:87–95 (in Russ.). https://doi.org/10.18565/aig.2023.160

9. Baranovskaya EI. Maternal mortality in modern world. Obstetrics, Gynecology and Reproduction. 2022;16(3):296–305 (in Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2022.279

10. Andreeva MD, Frolov DV, Yakovleva DA, Bayanduryan EA. Assessing the actual application of clinical guidelines for preventing venous thromboembolic complications during pregnancy, childbirth, and postpartum period. Bulletin of Medical Science. 2023;2(30):116–122 (in Russ.). https://doi.org/10.31684/25418475-2023-2-116

11. Levakhina LI, Blokh AI, Pasechnik OA, Burashnikova IP, Anpilova NG. Impact of HIV infection and tuberculosis on life expectancy in Siberian Federal District regions. Fundamental'naya i klinicheskaya medicina. 2022;7(4): 63-71(in Russ.). https://doi.org/10.23946/2500-0764-2022-7-4-63-71

12. Aftab F, Ahmed I, Ahmed S, Ali SM, Amenga-Etego S, Ariff S, et al. Alliance for Maternal and Newborn Health Improvement (AMANHI) maternal morbidity study group. Direct maternal morbidity and the risk of pregnancy-related deaths, stillbirths, and neonatal deaths in South Asia and sub-Saharan Africa: A populationbased prospective cohort study in 8 countries. PLoS Medicine.2021;18(6):e1003644. https://doi.org/10.1371/journal.pmed.1003644

13. Konoplyannikov AG, Mikhaleva LM, Olenev AS, Kudryavtseva YaYu, Songolova EN, Gracheva NA, et al. Analysis of the structure of maternal mortality. Gynecology, Obstetrics and Perinatology. 2020;19(3):133–138 (in Russ.). https://doi.org/10.20953/1726-1678-2020-3-133-138

14. Olenev AS, Konoplyannikov AG, Vuchenovich YuD, Ziyadinov AA, Novikova VA, Radzinskii VE. Social disadvantage of pregnant women: the reverse side of the metropolis. Akusherstvo i ginekologiya. Novosti. Mneniya. Obuchenie. 2020;8:3:29:8–15. (In Russ.). https://doi.org/10.24411/2303-9698-2020-13001

15. Akhmadeev NR, Fatkullin IF, Nurmukhametova AI, Panteleeva BV. Ways of maternal mortality risk reduction in critical obstetric conditions. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie. 2024;12(Suppl):6–12. (in Russ.). https://doi.org/10.33029/2303-9698-2024-12-suppl-6-12

16. Tikhonova MS, Timofeev ES, Kazantseva AV. Analysis of trends in maternal mortality in the Russia, the Ural federal district, the Sverdlovsk Region for 2013-2021. Bulletin of UGMU. 2023;2:41–51. (in Russ.). EDN: https://elibrary.ru/UIOQPR

17. Remneva OV, Ershova EG, Molchanova IV. The development of organization of three-level system of obstetrics service in the region using information technologies. Health Care of the Russian Federation. 2018;62(4):181– 186. (in Russ.). https://doi.org/10.18821/0044-197Х-2018-62-4-181-186.


Review

For citations:


Molchanova I.V., Koliado O.V., Remneva O.V., Yaroshenko I.D., Volodina A.A. Audit of maternal mortality in a large agricultural region of south Siberia. Fundamental and Clinical Medicine. 2026;11(1):82-91. (In Russ.) https://doi.org/10.23946/2500-0764-2026-11-1-82-91

Views: 166

JATS XML


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2500-0764 (Print)
ISSN 2542-0941 (Online)